← CFB Terminal
#57Wake Forest
—
ACC
AT
#27Louisville
—
ACC
2026 week 4 · Friday, September 25, 2026 at 11:00 PM CT · L&N Federal Credit Union Stadium

Projection

Louisville by 10.2
Wake ForestSP+ 3.4#57
LouisvilleSP+ 11.1#27
SP+ difference plus 2.5 points for hosting. A model's number, not a betting line.

Series recent meetings

2022 Wake Forest 21 – 48 Louisville
2021 Louisville 34 – 37 Wake Forest
2020 Wake Forest 21 – 45 Louisville
2019 Louisville 62 – 59 Wake Forest
2018 Wake Forest 56 – 35 Louisville
2017 Louisville 32 – 42 Wake Forest
2016 Wake Forest 12 – 44 Louisville
2015 Louisville 20 – 19 Wake Forest
Last 8 meetings shown. Full all-time series sits on each team page.
Data: CollegeFootballData · terminal