| 14:40 | 1st & 10 | OWN 19 | Phil Mafah run for 3 yds to the CLEM 22 | +3 | -0.23 |
| 14:20 | 2nd & 7 | OWN 22 | Clemson Penalty, False Start (Marcus Tate) to the CLEM 17 | -5 | |
| 13:43 | 2nd & 12 | OWN 17 | Cade Klubnik pass complete to Phil Mafah for no gain to the CLEM 17 | 0 | -0.17 |
| 13:26 | 3rd & 12 | OWN 17 | Cade Klubnik pass complete to Phil Mafah for 3 yds to the CLEM 20 | +3 | -0.03 |
| 12:46 | 4th & 9 | OWN 20 | Aidan Swanson punt for 42 yds, downed at the LOU 38 |
| 12:40 | 1st & 10 | OWN 38 | Tyler Shough pass complete to Chris Bell for 8 yds to the LOU 46 | +8 | 1.03 |
| 12:18 | 2nd & 2 | OWN 46 | Isaac Brown run for 5 yds to the CLEM 49 for a 1ST down | +5 | 0.16 |
| 11:58 | 1st & 10 | OPP 49 | Tyler Shough pass incomplete to Ja'Corey Brooks | 0 | -1.10 |
| 11:37 | 2nd & 10 | OPP 49 | Tyler Shough pass complete to Isaac Brown for a loss of 3 yards to the LOU 48 | -3 | -1.55 |
| 11:01 | 3rd & 13 | OWN 48 | Tyler Shough pass complete to Ja'Corey Brooks for 22 yds to the CLEM 30 for a 1ST down | +22 | 3.59 |
| 10:25 | 1st & 10 | OPP 30 | Isaac Brown run for 2 yds to the CLEM 28 Isaac Brown fumbled, forced by Peter Woods, recovered by LOU Isaac Brown | +2 | -0.30 |
| 9:53 | 2nd & 8 | OPP 28 | Tyler Shough pass complete to Isaac Brown for 2 yds to the CLEM 26 | +2 | -0.35 |
| 9:16 | 3rd & 6 | OPP 26 | Louisville Penalty, False Start (Ahmari Huggins-Bruce) to the CLEM 31 | -5 | |
| 8:33 | 3rd & 11 | OPP 31 | Shough, Tyler pass complete to Bell, Chris for 7 yards to the CLEMSON24, PENALTY LOUISVILLE illegal formation 5 yards to the CLEMSON36, NO PLAY. | -5 | |
| 8:11 | 3rd & 16 | OPP 36 | Tyler Shough pass complete to Mark Redman for 13 yds to the CLEM 23 | +13 | 1.66 |
| 7:33 | 4th & 3 | OPP 23 | Brock Travelstead 40 yd FG MISSED |
| 7:33 | 1st & 10 | OWN 23 | Louisville Penalty, Delay of Game (Dezmond Tell) to the CLEM 28 | +5 | |
| 7:25 | 1st & 5 | OWN 28 | Cade Klubnik pass incomplete | 0 | -1.27 |
| 7:14 | 2nd & 5 | OWN 28 | Cade Klubnik pass complete to Antonio Williams for a loss of 3 yards to the CLEM 25 | -3 | -0.94 |
| 6:39 | 3rd & 8 | OWN 25 | Cade Klubnik pass incomplete to T.J. Moore | 0 | -0.20 |
| 6:30 | 4th & 8 | OWN 25 | Aidan Swanson punt for 43 yds , Ahmari Huggins-Bruce returns for 5 yds to the LOU 37 |
| 6:25 | 1st & 10 | OWN 37 | Chris Bell run for 47 yds to the CLEM 16 for a 1ST down | +47 | 2.48 |
| 5:56 | 1st & 10 | OPP 16 | Tyler Shough pass complete to Mark Redman for 6 yds to the CLEM 10 | +6 | 0.18 |
| 5:33 | 2nd & 4 | OPP 10 | Tyler Shough pass complete to Ja'Corey Brooks for 3 yds to the CLEM 7 | +3 | -0.13 |
| 4:59 | 3rd & 1 | OPP 7 | Timeout Louisville, clock 04:59 | ||
| 4:59 | 3rd & 1 | OPP 7 | Clemson Penalty, Delay of Game (DeMonte Capehart) to the CLEM 3 for a 1ST down | +4 | |
| 4:54 | 1st & 3 | OPP 3 | Tyler Shough pass incomplete to Nate Kurisky | 0 | -0.75 |
| 4:48 | 2nd & 3 | OPP 3 | Tyler Shough pass incomplete to Jahlil McClain | 0 | -0.41 |
| 4:42 | 3rd & 3 | OPP 3 | Tyler Shough pass incomplete to Chris Bell | 0 | -0.29 |
| 4:39 | 4th & 3 | OPP 3 | Brock Travelstead 21 Yd Field Goal |
| 4:31 | 1st & 10 | OWN 25 | Phil Mafah run for 2 yds to the CLEM 27 | +2 | -0.45 |
| 4:03 | 2nd & 8 | OWN 27 | Cade Klubnik pass incomplete to Bryant Wesco Jr. | 0 | -0.48 |
| 3:51 | 3rd & 8 | OWN 27 | Cade Klubnik pass complete to Bryant Wesco Jr. for 8 yds to the CLEM 35 for a 1ST down | +8 | 1.77 |
| 3:30 | 1st & 10 | OWN 35 | Phil Mafah run for 8 yds to the CLEM 43 | +8 | 1.04 |
| 3:07 | 2nd & 2 | OWN 43 | Cade Klubnik pass complete to Antonio Williams for a loss of 1 yard to the CLEM 42 | -1 | -1.59 |
| 2:31 | 3rd & 3 | OWN 42 | Cade Klubnik pass complete to Bryant Wesco Jr. for 2 yds to the CLEM 44 | +2 | -0.52 |
| 1:47 | 4th & 1 | OWN 44 | Phil Mafah run for 3 yds to the CLEM 47 for a 1ST down | +3 | 2.22 |
| 1:26 | 1st & 10 | OWN 47 | Cade Klubnik pass complete to T.J. Moore for 22 yds to the LOU 31 for a 1ST down | +22 | 1.25 |
| 1:07 | 1st & 10 | OPP 31 | Cade Klubnik run for 6 yds to the LOU 25 | +6 | 0.21 |
| 0:43 | 2nd & 4 | OPP 25 | Cade Klubnik pass complete to T.J. Moore for 13 yds to the LOU 12 for a 1ST down | +13 | 0.10 |
| 0:16 | 1st & 10 | OPP 12 | Antonio Williams 12 Yd pass from Cade Klubnik (Nolan Hauser Kick) | +12 | 2.53 |
| 0:00 | 1st & 10 | OWN 21 | Isaac Brown run for 1 yd to the LOU 22 | +1 | -0.49 |
| 0:00 | OWN 21 | End of 1st Quarter | |||
| 14:54 | 2nd & 9 | OWN 22 | Tyler Shough pass incomplete Louisville Penalty, Illegal Shift (Jaleel Skinner) declined | 0 | -0.33 |
| 14:42 | 3rd & 9 | OWN 22 | Tyler Shough pass complete to Chris Bell for 13 yds to the LOU 35 for a 1ST down | +13 | 1.91 |
| 14:25 | 1st & 10 | OWN 35 | Tyler Shough pass incomplete to Chris Bell | 0 | -1.01 |
| 14:23 | 2nd & 10 | OWN 35 | Louisville Penalty, False Start (Mark Redman) to the LOU 30 | -5 | |
| 14:18 | 2nd & 15 | OWN 30 | Tyler Shough pass incomplete to Nate Kurisky | 0 | -0.29 |
| 14:14 | 3rd & 15 | OWN 30 | Tyler Shough pass incomplete to Ja'Corey Brooks | 0 | -0.13 |
| 14:02 | 4th & 15 | OWN 30 | Carter Schwartz punt for 44 yds, downed at the CLEM 26 |
| 13:53 | 1st & 10 | OWN 26 | Cade Klubnik run for 6 yds to the CLEM 32 | +6 | 0.34 |
| 13:17 | 2nd & 4 | OWN 32 | Cade Klubnik run for 9 yds to the CLEM 41 for a 1ST down | +9 | 1.01 |
| 12:37 | 1st & 10 | OWN 41 | Cade Klubnik pass complete to Bryant Wesco Jr. for 9 yds to the 50 yard line | +9 | 1.32 |
| 12:07 | 2nd & 1 | 50 | Phil Mafah run for 3 yds to the LOU 47 for a 1ST down | +3 | -0.28 |
| 11:27 | 1st & 10 | OPP 47 | Cade Klubnik pass complete to Jake Briningstool for 7 yds to the LOU 40 | +7 | 0.54 |
| 11:11 | 2nd & 3 | OPP 40 | Cade Klubnik run for 2 yds to the LOU 38 | +2 | -0.57 |
| 10:34 | 3rd & 1 | OPP 38 | Phil Mafah run for 1 yd to the LOU 37 for a 1ST down | +1 | 0.59 |
| 10:05 | 1st & 10 | OPP 37 | Cade Klubnik pass incomplete to Bryant Wesco Jr. | 0 | -0.75 |
| 10:00 | 2nd & 10 | OPP 37 | Phil Mafah run for 2 yds to the LOU 35 | +2 | -0.53 |
| 9:50 | 3rd & 8 | OPP 35 | Cade Klubnik pass complete to Tristan Leigh for a loss of 9 yards to the LOU 44 | -9 | -2.46 |
| 8:35 | 4th & 17 | OPP 44 | Aidan Swanson punt for 36 yds, fair catch by Ahmari Huggins-Bruce at the LOU 8 |
| 8:15 | 1st & 10 | OWN 8 | Isaac Brown run for 23 yds to the LOU 31 for a 1ST down Clemson Penalty, Horse Collar Tackle (Jeadyn Lukus) to the LOU 46 for a 1ST down | +38 | 2.66 |
| 8:00 | 1st & 10 | OWN 46 | Isaac Brown run for 3 yds to the LOU 49 | +3 | -0.42 |
| 7:35 | 2nd & 7 | OWN 49 | Tyler Shough pass incomplete to Mark Redman | 0 | -1.12 |
| 7:30 | 3rd & 7 | OWN 49 | Shough, Tyler pass incomplete to Brooks, Ja'Corey, PENALTY CLEMSON pass interference (Terrell, Avieon) 15 yards to the CLEMSON36, NO PLAY, 1ST DOWN LOUISVILLE. | +15 | |
| 7:18 | 1st & 10 | OPP 36 | Tyler Shough pass complete to Duke Watson for 31 yds to the CLEM 5 for a 1ST down | +31 | 1.13 |
| 6:45 | 1st & 5 | OPP 5 | Duke Watson run for 1 yd to the CLEM 4 | +1 | -0.45 |
| 6:15 | 2nd & 4 | OPP 4 | Tyler Shough pass complete to Isaac Brown for no gain to the CLEM 4 | 0 | -0.36 |
| 5:42 | 3rd & 4 | OPP 4 | Tyler Shough 4 Yd Run (Brock Travelstead Kick) | +4 | 2.70 |
| 5:32 | 1st & 10 | OWN 18 | Cade Klubnik pass incomplete to T.J. Moore | 0 | -0.51 |
| 5:23 | 2nd & 10 | OWN 18 | Phil Mafah run for 24 yds to the CLEM 42 for a 1ST down | +24 | 2.43 |
| 5:00 | 1st & 10 | OWN 42 | Phil Mafah run for 2 yds to the CLEM 44 | +2 | -0.69 |
| 4:26 | 2nd & 8 | OWN 44 | Phil Mafah run for 6 yds to the 50 yard line | +6 | 0.35 |
| 3:42 | 3rd & 2 | 50 | Cade Klubnik pass complete to Bryant Wesco Jr. for 5 yds to the LOU 45 for a 1ST down | +5 | 1.42 |
| 3:30 | 1st & 10 | OPP 45 | Cade Klubnik run for 12 yds to the LOU 33 for a 1ST down | +12 | 0.57 |
| 2:23 | 1st & 10 | OPP 33 | Cole Turner run for 1 yd to the LOU 32 | +1 | -0.48 |
| 1:56 | 2nd & 9 | OPP 32 | Cade Klubnik pass incomplete | 0 | -0.81 |
| 1:53 | 3rd & 9 | OPP 32 | Cade Klubnik pass incomplete to T.J. Moore | 0 | -1.01 |
| 1:43 | 4th & 9 | OPP 32 | Nolan Hauser 49 yd FG BLOCKED blocked by Stanquan Clark Hauser, Nolan field goal attempt from 49 blocked, recovered by LOUISVILLE McDonald, Tamarion at LOUISVILLE47 spot at LOUISVILLE47 (blocked by Clark, Stanquan), Clark, Stanquan for 6 yards to the CLEMSON47. Stanquan Clark return for 6 yds to the CLEM 47 |
| 1:38 | 1st & 10 | OPP 47 | Isaac Brown run for 12 yds to the CLEM 35 for a 1ST down | +12 | 0.64 |
| 1:23 | 1st & 10 | OPP 35 | Isaac Brown run for 23 yds to the CLEM 12 for a 1ST down | +23 | 0.44 |
| 1:19 | 1st & 10 | OPP 12 | Tyler Shough pass incomplete to Ahmari Huggins-Bruce | 0 | -0.30 |
| 1:09 | 2nd & 10 | OPP 12 | Isaac Brown run for 7 yds to the CLEM 5 | +7 | 0.18 |
| 1:00 | 3rd & 3 | OPP 5 | Tyler Shough run for 4 yds to the CLEM 1 for a 1ST down | +4 | 1.71 |
| 0:43 | 1st & 1 | OPP 1 | Keyjuan Brown 1 Yd Run (Brock Travelstead Kick) | +1 | 0.94 |
| 0:36 | 1st & 10 | OWN 25 | Cade Klubnik pass complete to T.J. Moore for 5 yds to the CLEM 30 | +5 | 0.09 |
| 0:35 | 2nd & 5 | OWN 30 | Timeout Clemson, clock 00:35 | ||
| 0:29 | 2nd & 5 | OWN 30 | Cade Klubnik pass complete to Phil Mafah for 4 yds to the CLEM 34 | +4 | -0.12 |
| 0:27 | 3rd & 1 | OWN 34 | Phil Mafah run for 2 yds to the CLEM 36 for a 1ST down | +2 | 0.95 |
| 0:26 | 1st & 10 | OWN 36 | Timeout Clemson, clock 00:26 | ||
| 0:15 | 1st & 10 | OWN 36 | Cade Klubnik pass incomplete to Jake Briningstool | 0 | -1.04 |
| 0:09 | 2nd & 10 | OWN 36 | Cade Klubnik pass incomplete to Jake Briningstool | 0 | -0.63 |
| 0:00 | 3rd & 10 | OWN 36 | Cade Klubnik pass complete to Troy Stellato for 10 yds to the CLEM 46 for a 1ST down | +10 | 2.63 |
| 0:00 | OWN 36 | End of 2nd Quarter |
| 14:54 | 1st & 10 | OWN 25 | Isaac Brown run for 2 yds to the LOU 27 | +2 | -0.45 |
| 14:23 | 2nd & 8 | OWN 27 | Tyler Shough pass complete to Mark Redman for 9 yds to the LOU 36 for a 1ST down | +9 | 1.38 |
| 14:15 | 1st & 10 | OWN 36 | Isaac Brown run for 16 yds to the CLEM 48 for a 1ST down | +16 | 1.46 |
| 13:38 | 1st & 10 | OPP 48 | Tyler Shough pass complete to Ja'Corey Brooks for 6 yds to the CLEM 42 | +6 | 0.33 |
| 13:10 | 2nd & 4 | OPP 42 | Isaac Brown run for 7 yds to the CLEM 35 for a 1ST down | +7 | 0.38 |
| 12:44 | 1st & 10 | OPP 35 | Tyler Shough pass complete to Ahmari Huggins-Bruce for 13 yds to the CLEM 22 for a 1ST down | +13 | 0.32 |
| 12:27 | 1st & 10 | OPP 22 | Tyler Shough pass incomplete to Ja'Corey Brooks | 0 | -0.40 |
| 12:18 | 2nd & 10 | OPP 22 | Isaac Brown run for a loss of 3 yards to the CLEM 25 | -3 | -0.99 |
| 11:49 | 3rd & 13 | OPP 25 | Tyler Shough pass incomplete to Ahmari Huggins-Bruce | 0 | -0.95 |
| 11:45 | 4th & 13 | OPP 25 | Brock Travelstead 42 Yd Field Goal |
| 11:32 | 1st & 10 | OWN 25 | Cade Klubnik run for no gain to the CLEM 25 | 0 | -0.70 |
| 10:43 | 2nd & 10 | OWN 25 | Cade Klubnik sacked by Jordan Guerad and Ashton Gillotte for a loss of 8 yards to the CLEM 17 | -8 | -0.56 |
| 10:27 | 3rd & 18 | OWN 17 | Cade Klubnik pass incomplete to Jake Briningstool | 0 | -0.04 |
| 10:12 | 4th & 18 | OWN 17 | Aidan Swanson punt for 36 yds , Ja'Corey Brooks returns for 3 yds to the LOU 20 Louisville Penalty, Illegal Block (D'Angelo Hutchinson) to the LOU 40 |
| 10:05 | 1st & 10 | OWN 40 | Isaac Brown run for 1 yd to the LOU 41 | +1 | -0.91 |
| 9:33 | 2nd & 9 | OWN 41 | Tyler Shough pass complete to Ja'Corey Brooks for 11 yds to the CLEM 48 for a 1ST down | +11 | 1.98 |
| 9:10 | 1st & 10 | OPP 48 | Isaac Brown run for 2 yds to the CLEM 46 | +2 | -0.60 |
| 8:47 | 2nd & 8 | OPP 46 | Tyler Shough pass complete to Chris Bell for 14 yds to the CLEM 32 for a 1ST down | +14 | 1.41 |
| 8:19 | 1st & 10 | OPP 32 | Duke Watson run for 1 yd to the CLEM 31 | +1 | -0.46 |
| 7:54 | 2nd & 9 | OPP 31 | Tyler Shough pass complete to Cataurus Hicks for no gain to the CLEM 31 | 0 | -0.78 |
| 7:19 | 3rd & 9 | OPP 31 | Tyler Shough pass complete to Mark Redman for 8 yds to the CLEM 23 | +8 | 0.59 |
| 6:47 | 4th & 1 | OPP 23 | Brock Travelstead 40 Yd Field Goal |
| 6:38 | 1st & 10 | OWN 25 | Phil Mafah run for 5 yds to the CLEM 30 | +5 | 0.09 |
| 6:10 | 2nd & 5 | OWN 30 | Phil Mafah run for 3 yds to the CLEM 33 | +3 | -0.31 |
| 5:30 | 3rd & 2 | OWN 33 | Phil Mafah run for 1 yd to the CLEM 34 | +1 | -0.50 |
| 4:53 | 4th & 1 | OWN 34 | Phil Mafah run for a loss of 1 yard to the CLEM 33 | -1 | -0.20 |
| 4:46 | 1st & 10 | OPP 33 | Tyler Shough pass incomplete to Mark Redman | 0 | -0.64 |
| 4:33 | 2nd & 10 | OPP 33 | Tyler Shough run for 1 yd to the CLEM 32 | +1 | -0.65 |
| 3:59 | 3rd & 9 | OPP 32 | Tyler Shough pass incomplete to Chris Bell | 0 | -1.01 |
| 3:53 | 4th & 9 | OPP 32 | Brock Travelstead 49 Yd Field Goal |
| 3:47 | 1st & 10 | OWN 25 | Cade Klubnik run for 2 yds to the CLEM 27 | +2 | -0.45 |
| 3:10 | 2nd & 8 | OWN 27 | Phil Mafah run for 10 yds to the CLEM 37 for a 1ST down | +10 | 1.48 |
| 2:48 | 1st & 10 | OWN 37 | Clemson Penalty, Illegal Touching (Jake Briningstool) to the CLEM 37 | 0 | |
| 2:41 | 2nd & 10 | OWN 37 | Cade Klubnik pass complete to Antonio Williams for 4 yds to the CLEM 41 | +4 | -0.12 |
| 1:58 | 3rd & 6 | OWN 41 | Cade Klubnik pass complete to Antonio Williams for 6 yds to the CLEM 47 for a 1ST down | +6 | 2.14 |
| 1:15 | 1st & 10 | OWN 47 | Phil Mafah run for 14 yds to the LOU 39 for a 1ST down | +14 | 0.95 |
| 0:49 | 1st & 10 | OPP 39 | Cade Klubnik run for 7 yds to the LOU 32 | +7 | 0.44 |
| 0:14 | 2nd & 3 | OPP 32 | Cade Klubnik pass incomplete to Troy Stellato | 0 | -0.80 |
| 0:00 | 3rd & 3 | OPP 32 | Phil Mafah run for 11 yds to the LOU 21 for a 1ST down | +11 | 0.87 |
| 0:00 | OPP 32 | End of 3rd Quarter | |||
| 14:52 | 1st & 10 | OPP 21 | Phil Mafah run for 10 yds to the LOU 11 for a 1ST down | +10 | 0.11 |
| 14:08 | 1st & 10 | OPP 11 | Phil Mafah run for 2 yds to the LOU 9 | +2 | -0.17 |
| 13:25 | 2nd & 8 | OPP 9 | Cade Klubnik pass complete to Antonio Williams for 2 yds to the LOU 7 | +2 | -0.15 |
| 12:50 | 3rd & 6 | OPP 7 | Cade Klubnik pass incomplete to Bryant Wesco Jr. Clemson Penalty, Offensive Holding (Tristan Leigh) declined | 0 | -0.32 |
| 12:44 | 4th & 6 | OPP 7 | Nolan Hauser 24 yd FG BLOCKED blocked by D'Angelo Hutchinson Hauser, Nolan field goal attempt from 24 blocked, recovered by LOUISVILLE TEAM at LOUISVILLE0 spot at LOUISVILLE0 (blocked by Hutchinson, D'Angelo), touchback. |
| 12:35 | 1st & 10 | OWN 20 | Isaac Brown run for 3 yds to the LOU 23 | +3 | -0.24 |
| 11:52 | 2nd & 7 | OWN 23 | Isaac Brown run for no gain to the LOU 23 | 0 | -0.44 |
| 11:08 | 3rd & 7 | OWN 23 | Tyler Shough pass incomplete to Keyjuan Brown Louisville Penalty, Offensive Holding (Trevonte Sylvester) declined | 0 | -0.20 |
| 11:01 | 4th & 7 | OWN 23 | Carter Schwartz punt for 38 yds, fair catch by Antonio Williams at the CLEM 39 |
| 10:51 | 1st & 10 | OWN 39 | Cade Klubnik pass complete to Jake Briningstool for 7 yds to the CLEM 46 | +7 | 0.71 |
| 10:33 | 2nd & 3 | OWN 46 | Cade Klubnik pass incomplete to Bryant Wesco Jr. | 0 | -1.30 |
| 10:23 | 3rd & 3 | OWN 46 | Phil Mafah run for 1 yd to the CLEM 47 | +1 | -0.77 |
| 9:46 | 4th & 2 | OWN 47 | Cade Klubnik pass complete to Bryant Wesco Jr. for 6 yds to the LOU 47 for a 1ST down | +6 | 2.60 |
| 9:29 | 1st & 10 | OPP 47 | Cade Klubnik pass incomplete to Phil Mafah | 0 | -1.05 |
| 9:21 | 2nd & 10 | OPP 47 | Phil Mafah run for 17 yds to the LOU 30 for a 1ST down | +17 | 1.85 |
| 8:59 | 1st & 10 | OPP 30 | Cade Klubnik pass incomplete to Troy Stellato | 0 | -0.56 |
| 8:37 | 2nd & 10 | OPP 30 | Cade Klubnik run for 8 yds to the LOU 22 | +8 | 0.45 |
| 8:27 | 3rd & 2 | OPP 22 | Jay Haynes run for no gain to the LOU 22 | 0 | -0.64 |
| 7:56 | 4th & 2 | OPP 22 | Timeout Clemson, clock 07:56 | ||
| 7:45 | 4th & 2 | OPP 22 | Antonio Williams run for 7 yds to the LOU 15 for a 1ST down | +7 | 1.00 |
| 7:32 | 1st & 10 | OPP 15 | Phil Mafah run for 7 yds to the LOU 8 | +7 | 0.30 |
| 6:57 | 2nd & 3 | OPP 8 | Cade Klubnik pass incomplete to Antonio Williams | 0 | -0.43 |
| 6:46 | 3rd & 3 | OPP 8 | Cade Klubnik pass complete to Bryant Wesco Jr. for 4 yds to the LOU 4 for a 1ST down | +4 | 1.00 |
| 6:24 | 1st & 4 | OPP 4 | Phil Mafah run for 1 yd to the LOU 3 | +1 | -0.52 |
| 6:03 | 2nd & 3 | OPP 3 | Cade Klubnik pass incomplete to Antonio Williams | 0 | -0.41 |
| 6:00 | 3rd & 3 | OPP 3 | Phil Mafah 3 Yd Run (Nolan Hauser Kick) | +3 | 2.62 |
| 5:50 | 1st & 10 | OPP 45 | Isaac Brown 45 Yd Run (Brock Travelstead Kick) | +45 | 3.48 |
| 5:37 | 1st & 10 | OWN 25 | Cade Klubnik pass complete to Bryant Wesco Jr. for 19 yds to the CLEM 44 for a 1ST down | +19 | 1.71 |
| 5:20 | 1st & 10 | OWN 44 | Cade Klubnik pass complete to Antonio Williams for 7 yds to the LOU 49 | +7 | 0.67 |
| 5:02 | 2nd & 3 | OPP 49 | Phil Mafah run for 7 yds to the LOU 42 for a 1ST down | +7 | 0.40 |
| 4:40 | 1st & 10 | OPP 42 | Phil Mafah run for 23 yds to the LOU 19 for a 1ST down | +23 | 0.69 |
| 4:13 | 1st & 10 | OPP 19 | Cade Klubnik sacked by Myles Jernigan for a loss of 2 yards to the LOU 21 | -2 | -0.53 |
| 3:49 | 2nd & 12 | OPP 21 | Cade Klubnik pass complete to Adam Randall for 11 yds to the LOU 10 | +11 | 0.58 |
| 3:30 | 3rd & 1 | OPP 10 | Phil Mafah run for no gain to the LOU 10 | 0 | -0.41 |
| 3:20 | 4th & 1 | OPP 10 | Cade Klubnik run for 1 yd to the LOU 9 for a 1ST down | +1 | 0.55 |
| 2:50 | 1st & 9 | OPP 9 | Cade Klubnik pass incomplete to Adam Randall | 0 | -0.32 |
| 2:44 | 2nd & 9 | OPP 9 | Cade Klubnik pass complete to Jake Briningstool for 8 yds to the LOU 1 | +8 | 0.29 |
| 2:26 | 3rd & 1 | OPP 1 | Phil Mafah run for no gain to the LOU 1 | 0 | -0.33 |
| 2:07 | 4th & 1 | OPP 1 | Phil Mafah 1 Yd Run (Nolan Hauser Kick) | +1 | 2.79 |
| 2:06 | 1st & 10 | OPP 42 | Louisville Penalty, False Start (Renato Brown) to the CLEM 47 | -5 | |
| 1:57 | 1st & 15 | OPP 47 | Isaac Brown run for 1 yd to the CLEM 46 | +1 | -0.82 |
| 1:56 | 2nd & 14 | OPP 46 | Isaac Brown run for 3 yds to the CLEM 43 | +3 | -0.38 |
| 1:55 | 3rd & 11 | OPP 43 | Timeout Clemson, clock 01:55 | ||
| 1:52 | 3rd & 11 | OPP 43 | Isaac Brown run for a loss of 2 yards to the CLEM 45 | -2 | -1.14 |
| 1:51 | 4th & 13 | OPP 45 | Timeout Clemson, clock 01:51 | ||
| 1:43 | 4th & 13 | OPP 45 | Brady Hodges punt for 45 yds for a touchback |
| 1:39 | 1st & 10 | OWN 20 | Cade Klubnik pass incomplete to Jake Briningstool | 0 | -0.56 |
| 1:32 | 2nd & 10 | OWN 20 | Cade Klubnik pass incomplete to Adam Randall | 0 | -0.26 |
| 1:23 | 3rd & 10 | OWN 20 | Cade Klubnik pass complete to Phil Mafah for 12 yds to the CLEM 32 for a 1ST down | +12 | 1.69 |
| 1:11 | 1st & 10 | OWN 32 | Cade Klubnik pass complete to T.J. Moore for 11 yds to the CLEM 43 for a 1ST down | +11 | 1.05 |
| 0:53 | 1st & 10 | OWN 43 | Cade Klubnik pass complete to T.J. Moore for 12 yds to the LOU 45 for a 1ST down | +12 | 0.99 |
| 0:46 | 1st & 10 | OPP 45 | Cade Klubnik pass incomplete to Bryant Wesco Jr. | 0 | -1.00 |
| 0:38 | 2nd & 10 | OPP 45 | Cade Klubnik pass incomplete | 0 | -1.07 |
| 0:30 | 3rd & 10 | OPP 45 | Cade Klubnik pass complete to Adam Randall for 10 yds to the LOU 35 for a 1ST down | +10 | 2.57 |
| 0:21 | 1st & 10 | OPP 35 | Cade Klubnik pass complete to Olsen Patt-Henry for 8 yds to the LOU 27 | +8 | 0.56 |
| 0:15 | 2nd & 2 | OPP 27 | Cade Klubnik pass complete to Olsen Patt-Henry for 5 yds to the LOU 22 for a 1ST down | +5 | -0.24 |
| 0:11 | 1st & 10 | OPP 22 | Timeout Louisville, clock 00:11 | ||
| 0:08 | 1st & 10 | OPP 22 | Cade Klubnik pass incomplete to Adam Randall | 0 | -0.40 |
| 0:00 | 2nd & 10 | OPP 22 | Cade Klubnik pass complete to Phil Mafah for 9 yds to the LOU 13 | +9 | 0.45 |
| 0:00 | OPP 22 | End of 4th Quarter |
| 2 | sacks | 0 |
| 6 | plays for loss | 3 |
| 0 | takeaways | 0 |
| 3 | three-and-outs forced | 2 |
| 7 | explosive plays allowed | 8 |
| 4.46 | yards allowed / play | 6.53 |
| 3 of 12 | scoring drives allowed | 7 of 11 |
| Stanquan Clark | 13 (9) | |
| D'Angelo Hutchinson | 9 (5) | 2 PD |
| TJ Quinn | 8 (4) | |
| Ashton Gillotte | 7 (4) | 0.5 sk · 0.5 TFL |
| Quincy Riley | 7 (5) | 2 TFL · 1 PD |
| M.J. Griffin | 6 (5) | 0.5 TFL |
| Tahveon Nicholson | 5 (4) | 1 PD |
| Corey Thornton | 5 (5) |
| Wade Woodaz | 11 (8) | |
| Jeadyn Lukus | 6 (6) | 1 TFL · 1 PD |
| Kylon Griffin | 5 (4) | |
| R.J. Mickens | 4 (3) | 1 TFL |
| Avieon Terrell | 3 (3) | |
| Khalil Barnes | 3 (3) | |
| DeMonte Capehart | 2 (2) | |
| Sammy Brown | 2 (2) |
| 4 of 5 | field goals | 0 of 2 |
| 3 | punts | 4 |
| 42.3 | punt average | 39.3 |
| 0 | punts inside the 20 | 1 |
| 29 | return yards | 32 |
| own 37 | average drive start | own 25 |
| K | Brock Travelstead | 4/5 FG · long 49 · 3/3 XP |
| P | Carter Schwartz | 2 punts · 41.0 avg |
| P | Brady Hodges | 1 punt · 45.0 avg · 1 TB |
| KR | Ja'Corey Brooks | 1 ret · 21 yds · long 21 |
| PR | Ja'Corey Brooks | 1 ret · 3 yds · long 3 |
| PR | Ahmari Huggins-Bruce | 1 ret · 5 yds · long 5 |
| K | Nolan Hauser | 0/2 FG · 3/3 XP |
| P | Aidan Swanson | 4 punts · 39.3 avg · 1 in 20 |
| KR | Jay Haynes | 2 ret · 32 yds · long 18 |
| 58 | plays | 101 |
| 379 | yards | 450 |
| 11 | drives | 12 |
| 40% | success rate | 51% |
| 12.22 | total PPA | 22.1 |
| Q1 | Brock Travelstead 21 Yd Field Goal | 3–0 |
| Q1 | Antonio Williams 12 Yd pass from Cade Klubnik (Nolan Hauser Kick) | 7–3 |
| Q2 | Tyler Shough 4 Yd Run (Brock Travelstead Kick) | 10–7 |
| Q2 | Keyjuan Brown 1 Yd Run (Brock Travelstead Kick) | 17–7 |
| Q3 | Brock Travelstead 42 Yd Field Goal | 20–7 |
| Q3 | Brock Travelstead 40 Yd Field Goal | 23–7 |
| Q3 | Brock Travelstead 49 Yd Field Goal | 26–7 |
| Q4 | Phil Mafah 3 Yd Run (Nolan Hauser Kick) | 14–26 |
| Q4 | Isaac Brown 45 Yd Run (Brock Travelstead Kick) | 33–14 |
| Q4 | Phil Mafah 1 Yd Run (Nolan Hauser Kick) | 21–33 |
| Q1 | Tyler Shough pass complete to Ja'Corey Brooks for 22 yds to the CLEM 30 for a 1ST down | 3.59 |
| Q4 | Isaac Brown 45 Yd Run (Brock Travelstead Kick) | 3.48 |
| Q4 | Phil Mafah 1 Yd Run (Nolan Hauser Kick) | 2.79 |
| Q2 | Tyler Shough 4 Yd Run (Brock Travelstead Kick) | 2.70 |
| Q2 | Isaac Brown run for 23 yds to the LOU 31 for a 1ST down Clemson Penalty, Horse Collar⦠| 2.66 |
| Q2 | Cade Klubnik pass complete to Troy Stellato for 10 yds to the CLEM 46 for a 1ST down | 2.63 |
| 2025 | Clemson 20 – 19 Louisville |
| 2022 | Louisville 16 – 31 Clemson |
| 2021 | Clemson 30 – 24 Louisville |
| 2019 | Clemson 45 – 10 Louisville |
| 2018 | Louisville 16 – 77 Clemson |
| 2017 | Clemson 47 – 21 Louisville |
| 2016 | Louisville 36 – 42 Clemson |
| 2015 | Clemson 20 – 17 Louisville |