| 14:42 | 1st & 10 | OWN 35 | Lamar Jackson pass complete to Jaylen Smith for 4 yds Jaylen Smith fumbled, forced by Brad Watson, recovered by WFrst Wendell Dunn | -1.76 |
| 14:30 | 1st & 10 | OPP 39 | Cade Carney run for 2 yds to the Lvile 37 | +2 | -0.44 |
| 14:00 | 2nd & 8 | OPP 37 | Cade Carney run for 3 yds to the Lvile 34 | +3 | -0.31 |
| 13:20 | 3rd & 5 | OPP 34 | John Wolford run for 3 yds to the Lvile 31 | +3 | -0.35 |
| 13:00 | 4th & 2 | OPP 31 | Tyler Bell run for 2 yds to the Lvile 29 for a 1ST down LOUISVILLE Penalty, Unsportsmanlike Conduct (Zykiesis Cannon) to the Lvile 14 for a 1ST down | +17 | 1.69 |
| 12:40 | 1st & 10 | OPP 14 | Cade Carney run for 1 yd to the Lvile 13 | +1 | -0.25 |
| 12:19 | 2nd & 9 | OPP 13 | Timeout WAKE FOREST, clock 12:19 | ||
| 12:12 | 2nd & 9 | OPP 13 | John Wolford pass incomplete to Alex Bachman | 0 | -0.32 |
| 11:45 | 3rd & 9 | OPP 13 | John Wolford sacked by DeAngelo Brown and Drew Bailey for a loss of 6 yards to the Lvile 19 | -6 | -1.52 |
| 11:24 | 4th & 15 | OPP 19 | Mike Weaver 37 yd FG GOOD | 0.64 |
| 11:18 | 1st & 10 | OWN 25 | Lamar Jackson pass incomplete to Jamari Staples | 0 | -0.70 |
| 11:05 | 2nd & 10 | OWN 25 | Brandon Radcliff run for 1 yd to the Lvile 26 | +1 | -0.29 |
| 10:30 | 3rd & 9 | OWN 26 | Lamar Jackson sacked by Chris Stewart for a loss of 1 yard to the Lvile 25 | -1 | -0.21 |
| 9:58 | 4th & 10 | OWN 25 | Mason King punt for 42 yds , Jessie Bates III returns for 6 yds to the WFrst 39 |
| 9:50 | 1st & 10 | OWN 39 | Cade Carney run for 3 yds to the WFrst 42 | +3 | -0.43 |
| 9:17 | 2nd & 7 | OWN 42 | Cade Carney run for 9 yds to the Lvile 49 for a 1ST down | +9 | 1.52 |
| 9:00 | 1st & 10 | OPP 49 | John Wolford pass complete to Cortez Lewis for 16 yds to the Lvile 33 for a 1ST down | +16 | 0.86 |
| 8:30 | 1st & 10 | OPP 33 | Cade Carney run for 4 yds to the Lvile 29 | +4 | -0.06 |
| 7:53 | 2nd & 6 | OPP 29 | Cade Carney run for 10 yds to the Lvile 19 for a 1ST down | +10 | 0.36 |
| 7:19 | 1st & 10 | OPP 19 | Cade Carney run for 4 yds to the Lvile 15 | +4 | -0.02 |
| 6:40 | 2nd & 6 | OPP 15 | WAKE FOREST Penalty, False Start (Ryan Anderson) to the Lvile 20 | -5 | |
| 6:30 | 2nd & 11 | OPP 20 | John Wolford sacked by James Hearns for a loss of 7 yards to the Lvile 27 | -7 | -1.69 |
| 5:33 | 3rd & 18 | OPP 27 | John Wolford pass incomplete to Cam Serigne | 0 | -0.99 |
| 5:27 | 4th & 18 | OPP 27 | Mike Weaver 45 yd FG GOOD | 1.73 |
| 5:10 | 1st & 10 | OWN 25 | Lamar Jackson sacked by Marquel Lee for a loss of 5 yards to the Lvile 20 | -5 | -1.07 |
| 4:30 | 2nd & 15 | OWN 20 | Lamar Jackson run for 1 yd to the Lvile 21 | +1 | -0.13 |
| 3:55 | 3rd & 14 | OWN 21 | Lamar Jackson sacked by Duke Ejiofor for a loss of 9 yards to the Lvile 12 | -9 | -0.13 |
| 3:19 | 4th & 23 | OWN 12 | Mason King punt for 45 yds, fair catch by Jessie Bates III at the WFrst 43 |
| 3:00 | 1st & 10 | OWN 43 | John Wolford pass complete to Matt Colburn for 15 yds to the Lvile 42 for a 1ST down | +15 | 1.17 |
| 2:50 | 1st & 10 | OPP 42 | WAKE FOREST Penalty, False Start (Ryan Anderson) to the Lvile 47 | -5 | |
| 2:25 | 1st & 15 | OPP 47 | John Wolford run for 1 yd to the Lvile 46 | +1 | -0.82 |
| 1:59 | 2nd & 14 | OPP 46 | John Wolford pass complete to Cortez Lewis for 17 yds to the Lvile 29 for a 1ST down | +17 | 2.30 |
| 1:26 | 1st & 10 | OPP 29 | Cade Carney run for a loss of 3 yards to the Lvile 32 Cade Carney fumbled, forced by DeAngelo Brown, recovered by Lvile Keith Kelsey | -4.21 |
| 1:15 | 1st & 10 | OWN 32 | Lamar Jackson pass complete to James Quick for 7 yds to the Lvile 39 | +7 | 0.69 |
| 0:54 | 2nd & 3 | OWN 39 | Lamar Jackson run for 6 yds to the Lvile 45 for a 1ST down | +6 | 0.55 |
| 0:25 | 1st & 10 | OWN 45 | Brandon Radcliff run for 6 yds to the WFrst 49 | +6 | 0.38 |
| 0:05 | 2nd & 4 | OPP 49 | Brandon Radcliff run for 12 yds to the WFrst 37 for a 1ST down | +12 | 0.84 |
| 0:00 | OWN 0 | End of 1st Quarter | |||
| 14:52 | 1st & 10 | OPP 37 | Lamar Jackson run for 17 yds to the WFrst 20 for a 1ST down | +17 | 0.43 |
| 14:35 | 1st & 10 | OPP 20 | Brandon Radcliff run for a loss of 2 yards to the WFrst 22 Brandon Radcliff fumbled, recovered by WFrst Josh Okonye | -4.38 |
| 14:30 | 1st & 10 | OWN 22 | Matt Colburn run for 6 yds to the WFrst 28 | +6 | 0.31 |
| 13:50 | 2nd & 4 | OWN 28 | Matt Colburn run for a loss of 1 yard to the WFrst 27 | -1 | -0.88 |
| 13:13 | 3rd & 5 | OWN 27 | John Wolford run for 25 yds to the Lvile 48 for a 1ST down | +25 | 3.16 |
| 12:35 | 1st & 10 | OPP 48 | Matt Colburn run for 1 yd to the Lvile 47 | +1 | -0.84 |
| 12:00 | 2nd & 9 | OPP 47 | Matt Colburn run for 14 yds to the Lvile 33 for a 1ST down | +14 | 1.62 |
| 11:15 | 1st & 10 | OPP 33 | Matt Colburn run for no gain to the Lvile 33 | 0 | -0.64 |
| 11:00 | 2nd & 10 | OPP 33 | Matt Colburn run for no gain to the Lvile 33 | 0 | -0.86 |
| 10:15 | 3rd & 10 | OPP 33 | John Wolford pass complete to Tyler Bell for 15 yds to the Lvile 18 for a 1ST down | +15 | 1.80 |
| 9:45 | 1st & 10 | OPP 18 | Matt Colburn run for a loss of 3 yards to the Lvile 21 | -3 | -0.60 |
| 9:20 | 2nd & 13 | OPP 21 | Matt Colburn run for 3 yds to the Lvile 18 | +3 | -0.17 |
| 8:50 | 3rd & 10 | OPP 18 | Tyler Bell run for 3 yds to the Lvile 15 | +3 | -0.21 |
| 8:19 | 4th & 7 | OPP 15 | Mike Weaver 33 yd FG GOOD | -0.42 |
| 8:04 | 1st & 10 | OWN 27 | Lamar Jackson pass incomplete to James Quick | 0 | -0.77 |
| 7:52 | 2nd & 10 | OWN 27 | Lamar Jackson run for 25 yds to the WFrst 48 Lamar Jackson fumbled, forced by Jessie Bates III, recovered by WFrst Amari Henderson | -0.30 |
| 7:42 | 1st & 10 | OWN 48 | Wolford, John rush for 21 yards to the LOUISVILLE31, PENALTY WAKEFOREST holding (Osterhage, Patrick) 10 yards to the WAKEFOREST38, NO PLAY. | -10 | |
| 7:15 | 1st & 20 | OWN 38 | Cade Carney run for 2 yds to the WFrst 40 | +2 | -0.39 |
| 6:41 | 2nd & 18 | OWN 40 | John Wolford pass complete to Alex Bachman for 8 yds to the WFrst 48 | +8 | 0.48 |
| 6:09 | 3rd & 10 | OWN 48 | John Wolford run for 15 yds to the Lvile 37 for a 1ST down | +15 | 3.08 |
| 5:37 | 1st & 10 | OPP 37 | John Wolford pass incomplete to Cortez Lewis | 0 | -0.75 |
| 5:00 | 2nd & 10 | OPP 37 | Cade Carney run for no gain to the Lvile 37 | 0 | -0.97 |
| 4:50 | 3rd & 10 | OPP 37 | John Wolford pass complete to Tabari Hines for 11 yds to the Lvile 26 for a 1ST down | +11 | 2.05 |
| 4:00 | 1st & 10 | OPP 26 | Cade Carney run for 1 yd to the Lvile 25 | +1 | -0.36 |
| 3:20 | 2nd & 9 | OPP 25 | John Wolford run for 5 yds to the Lvile 20 | +5 | 0.05 |
| 2:53 | 3rd & 4 | OPP 20 | John Wolford pass incomplete to Alex Bachman | 0 | -0.60 |
| 2:49 | 4th & 4 | OPP 20 | Mike Weaver 38 yd FG GOOD | -0.37 |
| 2:40 | 1st & 10 | OWN 23 | Lamar Jackson pass complete to Traveon Samuel for 20 yds to the Lvile 43 for a 1ST down | +20 | 1.75 |
| 2:17 | 1st & 10 | OWN 43 | Lamar Jackson run for 5 yds to the Lvile 48 | +5 | 0.11 |
| 2:03 | 2nd & 5 | OWN 48 | Lamar Jackson pass incomplete to Jamari Staples | 0 | -1.20 |
| 2:03 | 3rd & 5 | OWN 48 | Timeout WAKE FOREST, clock 02:03 | ||
| 1:55 | 3rd & 5 | OWN 48 | Lamar Jackson pass complete to Jeremy Smith for 15 yds to the WFrst 37 for a 1ST down | +15 | 2.50 |
| 1:35 | 1st & 10 | OPP 37 | Lamar Jackson sacked by Willie Yarbary for a loss of 5 yards to the WFrst 42 | -5 | -1.77 |
| 1:15 | 2nd & 15 | OPP 42 | Lamar Jackson run for 14 yds to the WFrst 28 | +14 | 1.78 |
| 0:44 | 3rd & 1 | OPP 28 | Lamar Jackson run for 17 yds to the WFrst 11 for a 1ST down | +17 | 0.52 |
| 0:40 | 1st & 10 | OPP 11 | Lamar Jackson run for no gain to the WFrst 11 Lamar Jackson fumbled, recovered by Lvile Lamar Jackson | 0 | -0.29 |
| 0:37 | 2nd & 10 | OPP 11 | Timeout WAKE FOREST, clock 00:37 | ||
| 0:32 | 2nd & 10 | OPP 11 | Lamar Jackson pass incomplete to Jamari Staples | 0 | -0.29 |
| 0:22 | 3rd & 10 | OPP 11 | Lamar Jackson pass incomplete to Jamari Staples | 0 | -0.46 |
| 0:18 | 4th & 10 | OPP 11 | Blanton Creque 28 yd FG GOOD | -0.43 |
| 0:10 | 1st & 10 | OWN 41 | TEAM run for a loss of 2 yards to the WFrst 39 | -2 | -1.52 |
| 0:00 | OPP 0 | End of 2nd Quarter |
| 14:46 | 1st & 10 | OWN 29 | Wolford, John pass incomplete to Lewis, Cortez, PENALTY LOUISVILLE pass interference (Alexander, Jaire) 15 yards to the WAKEFOREST44, NO PLAY, 1ST DOWN WAKEFOREST. | +15 | |
| 14:40 | 1st & 10 | OWN 44 | Cade Carney run for 2 yds to the WFrst 46 | +2 | -0.68 |
| 14:00 | 2nd & 8 | OWN 46 | Cade Carney run for 3 yds to the WFrst 49 | +3 | -0.41 |
| 13:35 | 3rd & 5 | OWN 49 | John Wolford sacked by Devonte Fields for a loss of 2 yards to the WFrst 47 | -2 | -1.18 |
| 12:42 | 4th & 7 | OWN 47 | Dom Maggio punt for 38 yds, fair catch by Jaire Alexander at the Lvile 15 |
| 12:35 | 1st & 10 | OWN 15 | Lamar Jackson pass complete to Cole Hikutini for 11 yds to the Lvile 26 for a 1ST down | +11 | 0.61 |
| 12:08 | 1st & 10 | OWN 26 | Brandon Radcliff run for 1 yd to the Lvile 27 | +1 | -0.61 |
| 11:33 | 2nd & 9 | OWN 27 | Lamar Jackson pass incomplete | 0 | -0.43 |
| 11:22 | 3rd & 9 | OWN 27 | Lamar Jackson run for 6 yds to the Lvile 33 | +6 | 0.10 |
| 10:47 | 4th & 3 | OWN 33 | Mason King punt for 47 yds , Jessie Bates III returns for 29 yds to the WFrst 49 |
| 10:35 | 1st & 10 | OWN 49 | John Wolford pass complete to Cortez Lewis for 9 yds to the Lvile 42 | +9 | 1.12 |
| 10:18 | 2nd & 1 | OPP 42 | Matt Colburn run for 4 yds to the Lvile 38 for a 1ST down | +4 | -0.29 |
| 9:55 | 1st & 10 | OPP 38 | Tabari Hines run for a loss of 10 yards to the Lvile 48 | -10 | -2.86 |
| 9:15 | 2nd & 20 | OPP 48 | John Wolford pass complete to Cortez Lewis for a loss of 1 yard to the Lvile 49 | -1 | -0.81 |
| 8:50 | 3rd & 21 | OPP 49 | John Wolford pass complete to Tabari Hines for 12 yds to the Lvile 37 | +12 | 1.09 |
| 8:13 | 4th & 9 | OPP 37 | John Wolford pass incomplete to Scotty Washington | 0 | -1.33 |
| 8:05 | 1st & 10 | OWN 37 | Lamar Jackson run for 8 yds to the Lvile 45 | +8 | 1.04 |
| 7:30 | 2nd & 2 | OWN 45 | Brandon Radcliff run for 55 yds for a TD, (Blanton Creque KICK) | +55 | 4.01 |
| 7:16 | 1st & 10 | OWN 33 | Wolford, John pass incomplete, PENALTY LOUISVILLE holding 10 yards to the WAKEFOREST43, NO PLAY, 1ST DOWN WAKEFOREST. | +10 | |
| 7:05 | 1st & 10 | OWN 43 | Matt Colburn run for 1 yd to the WFrst 44 | +1 | -0.93 |
| 6:30 | 2nd & 9 | OWN 44 | Cade Carney run for 1 yd to the WFrst 45 | +1 | -0.77 |
| 5:51 | 3rd & 8 | OWN 45 | John Wolford pass incomplete to Chuck Wade | 0 | -0.64 |
| 5:41 | 4th & 8 | OWN 45 | Dom Maggio punt for 43 yds , Jaire Alexander returns for 5 yds to the Lvile 17 |
| 5:30 | 1st & 10 | OWN 17 | Lamar Jackson run for 55 yds to the WFrst 28 for a 1ST down | +55 | 3.77 |
| 5:10 | 1st & 10 | OPP 28 | Lamar Jackson pass incomplete to Jamari Staples | 0 | -0.51 |
| 5:03 | 2nd & 10 | OPP 28 | Lamar Jackson pass incomplete | 0 | -0.70 |
| 4:55 | 3rd & 10 | OPP 28 | Lamar Jackson run for 2 yds to the WFrst 26 | +2 | -0.53 |
| 4:21 | 4th & 8 | OPP 26 | Blanton Creque 43 yd FG MISSED |
| 4:15 | 1st & 10 | OWN 26 | John Wolford pass incomplete | 0 | -0.73 |
| 4:10 | 2nd & 10 | OWN 26 | Cade Carney run for 5 yds to the WFrst 31 | +5 | 0.05 |
| 3:45 | 3rd & 5 | OWN 31 | John Wolford pass complete to Cam Serigne for 11 yds to the WFrst 42 for a 1ST down | +11 | 2.13 |
| 3:30 | 1st & 10 | OWN 42 | Cade Carney run for 3 yds to the WFrst 45 | +3 | -0.43 |
| 3:12 | 2nd & 7 | OWN 45 | John Wolford pass complete to Tabari Hines for a loss of 1 yard to the WFrst 44 | -1 | -1.24 |
| 2:41 | 3rd & 8 | OWN 44 | John Wolford pass incomplete to Cortez Lewis | 0 | -0.61 |
| 2:30 | 4th & 8 | OWN 44 | Dom Maggio punt for 45 yds, downed at the Lvile 11 |
| 2:24 | 1st & 10 | OWN 11 | Lamar Jackson pass incomplete to Jamari Staples | 0 | -0.37 |
| 2:16 | 2nd & 10 | OWN 11 | Brandon Radcliff run for 27 yds to the Lvile 38 for a 1ST down | +27 | 2.18 |
| 1:49 | 1st & 10 | OWN 38 | Lamar Jackson run for 1 yd to the Lvile 39 | +1 | -0.89 |
| 1:16 | 2nd & 9 | OWN 39 | Lamar Jackson pass incomplete | 0 | -0.78 |
| 1:11 | 3rd & 9 | OWN 39 | Lamar Jackson pass incomplete to Jamari Staples | 0 | -0.42 |
| 1:04 | 4th & 9 | OWN 39 | Mason King punt for 33 yds, fair catch by Jessie Bates III at the WFrst 28 |
| 0:55 | 1st & 10 | OWN 28 | Matt Colburn run for 2 yds to the WFrst 30 | +2 | -0.51 |
| 0:30 | 2nd & 8 | OWN 30 | John Wolford run for no gain to the WFrst 30 | 0 | -0.56 |
| 0:00 | OPP 0 | End of 3rd Quarter | |||
| 14:50 | 3rd & 8 | OWN 30 | John Wolford sacked by James Hearns for a loss of 1 yard to the WFrst 29 | -1 | -0.30 |
| 14:09 | 4th & 9 | OWN 29 | Dom Maggio punt for 42 yds , Jaire Alexander returns for 6 yds to the Lvile 35 |
| 14:00 | 1st & 10 | OWN 35 | Lamar Jackson pass complete to Jamari Staples for 7 yds to the Lvile 42 | +7 | 0.71 |
| 13:35 | 2nd & 3 | OWN 42 | Lamar Jackson run for a loss of 4 yards to the Lvile 38 | -4 | -1.98 |
| 13:06 | 3rd & 7 | OWN 38 | Lamar Jackson pass complete to Traveon Samuel for 22 yds to the WFrst 40 for a 1ST down | +22 | 3.33 |
| 12:35 | 1st & 10 | OPP 40 | Lamar Jackson pass complete to Jamari Staples for 4 yds to the WFrst 36 | +4 | -0.09 |
| 12:00 | 2nd & 6 | OPP 36 | Lamar Jackson sacked by Willie Yarbary for a loss of 11 yards to the WFrst 47 | -11 | -3.12 |
| 11:39 | 3rd & 17 | OPP 47 | Lamar Jackson pass complete to Cole Hikutini for 13 yds to the WFrst 34 | +13 | 1.62 |
| 11:18 | 4th & 4 | OPP 34 | Lamar Jackson pass complete to Reggie Bonnafon for 12 yds to the WFrst 22 for a 1ST down | +12 | 2.13 |
| 10:57 | 1st & 10 | OPP 22 | Brandon Radcliff run for 15 yds to the WFrst 7 for a 1ST down | +15 | 0.45 |
| 10:35 | 1st & 7 | OPP 7 | Brandon Radcliff run for 7 yds for a TD, (Two-Point Conversion failed ) | +7 | 2.20 |
| 10:15 | 1st & 10 | OWN 40 | John Wolford sacked by DeAngelo Brown for a loss of 10 yards to the WFrst 30 | -10 | -2.32 |
| 9:53 | 2nd & 20 | OWN 30 | WAKE FOREST Penalty, False Start (-5 Yards) to the WFrst 25 | -5 | |
| 9:25 | 2nd & 25 | OWN 25 | John Wolford pass complete to Alex Bachman for 18 yds to the WFrst 43 | +18 | 1.07 |
| 9:06 | 3rd & 7 | OWN 43 | John Wolford pass incomplete to Alex Bachman | 0 | -0.62 |
| 8:58 | 4th & 7 | OWN 43 | Dom Maggio punt blocked by Devante Peete blocked by Devante Peete |
| 8:45 | 1st & 10 | OPP 43 | Lamar Jackson run for 17 yds to the WFrst 26 for a 1ST down | +17 | 0.63 |
| 8:28 | 1st & 10 | OPP 26 | Lamar Jackson pass complete to Jamari Staples for 7 yds to the WFrst 19 | +7 | 0.33 |
| 8:08 | 2nd & 3 | OPP 19 | Brandon Radcliff run for no gain to the WFrst 19 | 0 | -0.53 |
| 7:36 | 3rd & 3 | OPP 19 | Brandon Radcliff run for 19 yds for a TD, (Blanton Creque KICK) | +19 | 2.91 |
| 7:07 | 1st & 10 | OWN 25 | John Wolford sacked by Devonte Fields for a loss of 11 yards to the WFrst 14 | -11 | -1.24 |
| 6:52 | 2nd & 21 | OWN 14 | John Wolford pass complete to Alex Bachman for 11 yds to the WFrst 25 | +11 | 0.19 |
| 6:30 | 3rd & 10 | OWN 25 | John Wolford sacked by Devonte Fields for a loss of 14 yards to the WFrst 11 | -14 | -0.27 |
| 5:52 | 4th & 24 | OWN 11 | Dom Maggio punt for 26 yds, downed at the WFrst 37 |
| 5:45 | 1st & 10 | OPP 37 | Lamar Jackson run for 12 yds to the WFrst 25 for a 1ST down | +12 | 0.35 |
| 5:10 | 1st & 10 | OPP 25 | Lamar Jackson pass complete to Jaylen Smith for 11 yds to the WFrst 14 for a 1ST down | +11 | 0.15 |
| 4:55 | 1st & 10 | OPP 14 | Lamar Jackson run for 2 yds to the WFrst 12 | +2 | -0.18 |
| 4:25 | 2nd & 8 | OPP 12 | Lamar Jackson pass incomplete | 0 | -0.32 |
| 4:21 | 3rd & 8 | OPP 12 | Lamar Jackson pass complete to Jamari Staples for 10 yds to the WFrst 2 for a 1ST down | +10 | 1.83 |
| 4:05 | 1st & 2 | OPP 2 | Lamar Jackson pass complete to Cole Hikutini for 2 yds for a TD, (Blanton Creque KICK) | +2 | 1.21 |
| 3:53 | 1st & 10 | OWN 27 | Kyle Kearns pass incomplete | 0 | -0.77 |
| 3:44 | 2nd & 10 | OWN 27 | Kyle Kearns pass intercepted for a TD Ronald Walker return for 31 yds for a TD, (Blanton Creque KICK) | -7.30 |
| 3:25 | 1st & 10 | OWN 21 | Rocky Reid run for 4 yds to the WFrst 25 | +4 | -0.09 |
| 3:00 | 2nd & 6 | OWN 25 | Rocky Reid run for no gain to the WFrst 25 | 0 | -0.54 |
| 2:20 | 3rd & 6 | OWN 25 | Rocky Reid run for no gain to the WFrst 25 | 0 | -0.25 |
| 1:46 | 4th & 6 | OWN 25 | Dom Maggio punt for 27 yds, downed at the Lvile 48 |
| 1:40 | 1st & 10 | OWN 48 | Jeremy Smith run for 29 yds to the WFrst 23 for a 1ST down | +29 | 1.34 |
| 1:33 | 1st & 10 | OPP 23 | Jeremy Smith run for 8 yds to the WFrst 15 | +8 | 0.47 |
| 0:53 | 2nd & 2 | OPP 15 | Malik Williams run for 13 yds to the WFrst 2 for a 1ST down | +13 | 0.98 |
| 0:50 | 1st & 2 | OPP 2 | Malik Williams run for 2 yds for a TD, (Blanton Creque KICK) | +2 | 1.21 |
| 0:35 | 1st & 10 | OWN 27 | Rocky Reid run for 1 yd to the WFrst 28 | +1 | -0.64 |
| 0:00 | OPP 0 | End of 4th Quarter |
| 5 | sacks | 7 |
| 6 | plays for loss | 13 |
| 3 | takeaways | 2 |
| 2 | three-and-outs forced | 6 |
| 15 | explosive plays allowed | 7 |
| 7.86 | yards allowed / play | 3.22 |
| 6 of 14 | scoring drives allowed | 4 of 16 |
| Jessie Bates III | 13 (8) | |
| Josh Okonye | 8 (4) | |
| Marquel Lee | 4 (3) | 1 sk · 2 TFL |
| Duke Ejiofor | 4 (2) | 1 sk · 1 TFL |
| Thomas Brown | 4 (4) | 1 QH |
| Chris Stewart | 3 (1) | 1 sk · 1 TFL |
| Brad Watson | 3 (2) | 2 PD |
| Wendell Dunn | 3 (3) |
| Devonte Fields | 9 (7) | 3 sk · 4 TFL · 1 QH |
| Chucky Williams | 9 (7) | 1 TFL |
| Stacy Thomas | 8 (5) | 1 TFL |
| Keith Kelsey | 7 (4) | 1 QH |
| DeAngelo Brown | 6 (5) | 1.5 sk · 2.5 TFL |
| Drew Bailey | 6 (3) | 0.5 sk · 1.5 TFL |
| James Hearns | 4 (3) | 2 sk · 2 TFL · 3 QH |
| Ronald Walker | 4 (3) | 1 INT |
| 4 of 4 | field goals | 1 of 2 |
| 6 | punts | 4 |
| 36.8 | punt average | 41.8 |
| 0 | punts inside the 20 | 0 |
| 178 | return yards | 96 |
| own 35 | average drive start | own 31 |
| K | Mike Weaver | 4/4 FG · long 45 |
| P | Dom Maggio | 6 punts · 36.8 avg |
| KR | John Armstrong | 6 ret · 142 yds · long 28 |
| KR | Jack Freudenthal | 1 ret · 1 yds · long 1 |
| PR | Jessie Bates III | 2 ret · 35 yds · long 29 |
| K | Blanton Creque | 1/2 FG · long 28 · 5/5 XP |
| P | Mason King | 4 punts · 41.8 avg |
| KR | Malik Williams | 3 ret · 85 yds · long 35 |
| PR | Jaire Alexander | 2 ret · 11 yds · long 6 |
| PR | Devante Peete | 1 ret · 0 yds |
| 72 | plays | 59 |
| 232 | yards | 464 |
| 16 | drives | 13 |
| 22% | success rate | 53% |
| -18.21 | total PPA | 24.66 |
| Q1 | Mike Weaver 37 yd FG GOOD | 3–0 |
| Q1 | Mike Weaver 45 yd FG GOOD | 6–0 |
| Q2 | Mike Weaver 33 yd FG GOOD | 9–0 |
| Q2 | Mike Weaver 38 yd FG GOOD | 12–0 |
| Q2 | Blanton Creque 28 yd FG GOOD | 3–12 |
| Q3 | Brandon Radcliff run for 55 yds for a TD, (Blanton Creque KICK) | 10–12 |
| Q4 | Brandon Radcliff run for 7 yds for a TD, (Two-Point Conversion failed ) | 16–12 |
| Q4 | Brandon Radcliff run for 19 yds for a TD, (Blanton Creque KICK) | 23–12 |
| Q4 | Lamar Jackson pass complete to Cole Hikutini for 2 yds for a TD, (Blanton Creque KICK) | 30–12 |
| Q4 | Kyle Kearns pass intercepted for a TD Ronald Walker return for 31 yds for a TD, (Blanton Creque… | 12–37 |
| Q4 | Malik Williams run for 2 yds for a TD, (Blanton Creque KICK) | 44–12 |
| Q3 | Brandon Radcliff run for 55 yds for a TD, (Blanton Creque KICK) | 4.01 |
| Q3 | Lamar Jackson run for 55 yds to the WFrst 28 for a 1ST down | 3.77 |
| Q4 | Lamar Jackson pass complete to Traveon Samuel for 22 yds to the WFrst 40 for a 1ST down | 3.33 |
| Q2 | John Wolford run for 25 yds to the Lvile 48 for a 1ST down | 3.16 |
| Q2 | John Wolford run for 15 yds to the Lvile 37 for a 1ST down | 3.08 |
| Q4 | Brandon Radcliff run for 19 yds for a TD, (Blanton Creque KICK) | 2.91 |
| 2022 | Wake Forest 21 – 48 Louisville |
| 2021 | Louisville 34 – 37 Wake Forest |
| 2020 | Wake Forest 21 – 45 Louisville |
| 2019 | Louisville 62 – 59 Wake Forest |
| 2018 | Wake Forest 56 – 35 Louisville |
| 2017 | Louisville 32 – 42 Wake Forest |
| 2015 | Louisville 20 – 19 Wake Forest |
| 2014 | Wake Forest 10 – 20 Louisville |