| 14:55 | 1st & 10 | OWN 25 | Nathan Peterman pass incomplete to Aaron Mathews | 0 | -0.70 |
| 14:28 | 2nd & 10 | OWN 25 | Nathan Peterman pass complete to Jaymar Parrish for 44 yds to the Clem 31 for a 1ST down | +44 | 3.94 |
| 14:00 | 1st & 10 | OPP 31 | Nathan Peterman pass complete to Scott Orndoff for 8 yds to the Clem 23 | +8 | 0.52 |
| 13:39 | 2nd & 2 | OPP 23 | James Conner run for 8 yds to the Clem 15 for a 1ST down | +8 | -0.24 |
| 13:08 | 1st & 10 | OPP 15 | Nathan Peterman pass complete to George Aston for 15 yds for a TD, (Chris Blewitt KICK) | +15 | 2.56 |
| 12:58 | 1st & 10 | OWN 22 | Deshaun Watson pass complete to Hunter Renfrow for 9 yds to the Clem 31 | +9 | 1.17 |
| 12:30 | 2nd & 1 | OWN 31 | Deshaun Watson pass complete to Artavis Scott for 9 yds to the Clem 40 for a 1ST down | +9 | 0.34 |
| 12:17 | 1st & 10 | OWN 40 | Deshaun Watson pass incomplete to Deon Cain | 0 | -1.12 |
| 12:10 | 2nd & 10 | OWN 40 | Wayne Gallman run for 5 yds to the Clem 45 | +5 | 0.07 |
| 12:01 | 3rd & 5 | OWN 45 | Deshaun Watson pass complete to Jordan Leggett for 7 yds to the Pitt 48 for a 1ST down | +7 | 2.13 |
| 11:39 | 1st & 10 | OPP 48 | Deshaun Watson pass complete to Mike Williams for 31 yds to the Pitt 17 for a 1ST down | +31 | 1.11 |
| 11:22 | 1st & 10 | OPP 17 | Deshaun Watson pass complete to Artavis Scott for 4 yds to the Pitt 13 | +4 | -0.02 |
| 10:56 | 2nd & 6 | OPP 13 | Deshaun Watson pass intercepted, touchback. Ryan Lewis return for no gain | -4.40 |
| 10:49 | 1st & 10 | OWN 20 | James Conner run for no gain to the Pitt 20 | 0 | -0.56 |
| 10:18 | 2nd & 10 | OWN 20 | Nathan Peterman pass incomplete to Quadree Henderson | 0 | -0.26 |
| 10:09 | 3rd & 10 | OWN 20 | Nathan Peterman run for 4 yds to the Pitt 24 PITTSBURGH Penalty, Offensive Holding (Alex Officer) to the Pitt 14 | -6 | -0.17 |
| 9:39 | 3rd & 16 | OWN 14 | Dontez Ford run for 1 yd to the Pitt 15 | +1 | -0.03 |
| 9:12 | 4th & 15 | OWN 15 | Ryan Winslow punt for 39 yds , Ray-Ray McCloud returns for 3 yds to the Clem 49 |
| 9:00 | 1st & 10 | OWN 49 | Wayne Gallman run for 2 yds to the Pitt 49 | +2 | -0.64 |
| 8:40 | 2nd & 8 | OPP 49 | Deshaun Watson pass incomplete to Artavis Scott | 0 | -1.10 |
| 8:28 | 3rd & 8 | OPP 49 | Deshaun Watson pass complete to Mike Williams for 30 yds to the Pitt 19 for a 1ST down | +30 | 3.06 |
| 8:13 | 1st & 10 | OPP 19 | Wayne Gallman run for no gain to the Pitt 19 | 0 | -0.36 |
| 7:41 | 2nd & 10 | OPP 19 | Deshaun Watson pass complete to Artavis Scott for 18 yds to the Pitt 1 for a 1ST down | +18 | 2.03 |
| 7:19 | 1st & 1 | OPP 1 | Wayne Gallman run for 1 yd for a TD, (Greg Huegel KICK) | +1 | 0.94 |
| 6:41 | 1st & 10 | OWN 25 | Maurice Ffrench run for no gain to the Pitt 25 | 0 | -0.70 |
| 6:34 | 2nd & 10 | OWN 25 | Nathan Peterman pass complete to Scott Orndoff for 17 yds to the Pitt 42 for a 1ST down | +17 | 2.22 |
| 5:57 | 1st & 10 | OWN 42 | Nathan Peterman pass complete to George Aston for 14 yds to the Clem 44 for a 1ST down | +14 | 1.15 |
| 5:53 | 1st & 10 | OPP 44 | Nathan Peterman pass complete to James Conner for a loss of 2 yards to the Clem 46 | -2 | -1.42 |
| 5:28 | 2nd & 12 | OPP 46 | Nathan Peterman pass complete to James Conner for 46 yds for a TD, (Chris Blewitt KICK) | +46 | 4.84 |
| 5:12 | 1st & 10 | OWN 30 | C.J. Fuller run for no gain to the Clem 30 | 0 | -0.86 |
| 4:45 | 2nd & 10 | OWN 30 | Deshaun Watson pass complete to Deon Cain for 15 yds to the Clem 45 for a 1ST down | +15 | 2.28 |
| 4:10 | 1st & 10 | OWN 45 | Deshaun Watson run for 2 yds to the Clem 47 | +2 | -0.68 |
| 4:02 | 2nd & 8 | OWN 47 | Deshaun Watson pass incomplete to Ray-Ray McCloud | 0 | -1.05 |
| 3:55 | 3rd & 8 | OPP 47 | Deshaun Watson pass complete to Mike Williams for 18 yds to the CLEMSON 35 for a 1ST down PITTSBURGH Penalty, Roughing Passer (Ejuan Price) to the Pitt 20 for a 1ST down | +33 | 2.94 |
| 3:33 | 1st & 10 | OPP 20 | C.J. Fuller run for 6 yds to the Pitt 14 | +6 | 0.19 |
| 3:11 | 2nd & 4 | OPP 14 | Watson, Deshaun pass complete to Scott, Artavis for 14 yards to the PITTSBURGH0, PENALTY CLEMSON personal foul (Morris, Maverick) 15 yards to the PITTSBURGH29, NO PLAY. | -15 | |
| 2:47 | 2nd & 19 | OPP 29 | Deshaun Watson pass complete to Mike Williams for 7 yds to the Pitt 22 | +7 | 0.36 |
| 2:17 | 3rd & 12 | OPP 22 | Deshaun Watson pass complete to Mike Williams for 16 yds to the Pitt 6 for a 1ST down | +16 | 1.68 |
| 1:55 | 1st & goal | OPP 6 | Timeout PITTSBURGH, clock 01:55 | ||
| 1:50 | 1st & 6 | OPP 6 | Deshaun Watson pass incomplete to Hunter Renfrow | 0 | -0.48 |
| 1:20 | 2nd & 6 | OPP 6 | Wayne Gallman run for 5 yds to the Pitt 1 | +5 | 0.07 |
| 1:00 | 3rd & 1 | OPP 1 | Wayne Gallman run for no gain to the Pitt 1 | 0 | -0.33 |
| 0:40 | 4th & 1 | OPP 1 | Wayne Gallman run for 1 yd for a TD, (Greg Huegel KICK) | +1 | 2.79 |
| 0:30 | 1st & 10 | OWN 25 | James Conner run for 5 yds to the Pitt 30 | +5 | 0.09 |
| 0:10 | 2nd & 5 | OWN 30 | James Conner run for 16 yds to the Pitt 46 for a 1ST down | +16 | 1.80 |
| 0:00 | OPP 0 | End of 1st Quarter | |||
| 14:44 | 1st & 10 | OWN 46 | Quadree Henderson run for 1 yd to the Pitt 47 | +1 | -0.92 |
| 14:26 | 2nd & 9 | OWN 47 | James Conner run for 1 yd to the Pitt 48 | +1 | -0.82 |
| 13:56 | 3rd & 8 | OWN 48 | Nathan Peterman pass incomplete to Scott Orndoff | 0 | -0.73 |
| 13:48 | 4th & 8 | OWN 48 | Ryan Winslow punt for 52 yds for a touchback |
| 13:41 | 1st & 10 | OWN 20 | Deshaun Watson pass complete to Artavis Scott for 6 yds to the Clem 26 | +6 | 0.29 |
| 13:16 | 2nd & 4 | OWN 26 | Deshaun Watson pass incomplete to Hunter Renfrow | 0 | -0.71 |
| 13:09 | 3rd & 4 | OWN 26 | Deshaun Watson pass complete to Jordan Leggett for 29 yds to the Pitt 45 for a 1ST down | +29 | 3.33 |
| 12:55 | 1st & 10 | OPP 45 | Watson, Deshaun pass complete to Scott, Artavis for loss of 4 yards to the PITTSBURGH49, PENALTY CLEMSON holding (Anchrum, Tremayne) 10 yards to the CLEMSON45, NO PLAY. | -10 | |
| 12:22 | 1st & 20 | OWN 45 | Deshaun Watson pass complete to Wayne Gallman for a loss of 6 yards to the Clem 39 | -6 | -1.39 |
| 12:07 | 2nd & 26 | OWN 39 | Deshaun Watson pass incomplete to Deon Cain | 0 | -0.20 |
| 12:02 | 3rd & 26 | OWN 39 | Watson, Deshaun pass incomplete to Cain, Deon, PENALTY PITTSBURGH pass interference (Lewis, Ryan) 15 yards to the PITTSBURGH46, NO PLAY, 1ST DOWN CLEMSON. | +15 | |
| 11:55 | 1st & 10 | OPP 46 | Wayne Gallman run for 1 yd to the Pitt 45 | +1 | -0.79 |
| 11:30 | 2nd & 9 | OPP 45 | Deshaun Watson pass complete to Wayne Gallman for 10 yds to the Pitt 35 for a 1ST down | +10 | 1.36 |
| 11:07 | 1st & 10 | OPP 35 | Deshaun Watson pass incomplete to Artavis Scott | 0 | -0.69 |
| 11:00 | 2nd & 10 | OPP 35 | Deshaun Watson run for 6 yds to the Pitt 29 | +6 | 0.23 |
| 10:24 | 3rd & 4 | OPP 29 | Deshaun Watson pass complete to Ray-Ray McCloud for 14 yds to the Pitt 15 for a 1ST down | +14 | 0.88 |
| 10:06 | 1st & 10 | OPP 15 | Deshaun Watson pass complete to Mike Williams for 15 yds for a TD, (Greg Huegel KICK) | +15 | 2.56 |
| 9:58 | 1st & 10 | OWN 35 | Nathan Peterman pass incomplete to George Aston | 0 | -1.01 |
| 9:51 | 2nd & 10 | OWN 35 | Nathan Peterman pass incomplete to Jester Weah | 0 | -0.60 |
| 9:44 | 3rd & 10 | OWN 35 | Peterman, Nathan pass incomplete to Weah, Jester, PENALTY CLEMSON holding (Fields, Mark) 10 yards to the PITTSBURGH45, NO PLAY, 1ST DOWN PITTSBURGH. | +10 | |
| 9:33 | 1st & 10 | OWN 45 | Nathan Peterman pass complete to Scott Orndoff for 55 yds for a TD, (Chris Blewitt PAT MISSED) | +55 | 4.28 |
| 9:18 | 1st & 10 | OWN 26 | Wayne Gallman run for 8 yds to the Clem 34 | +8 | 0.93 |
| 8:33 | 2nd & 2 | OWN 34 | Deshaun Watson sacked by Jeremiah Taleni for a loss of 2 yards to the Clem 32 | -2 | -1.49 |
| 8:11 | 3rd & 4 | OWN 32 | Deshaun Watson pass complete to Jordan Leggett for 21 yds to the Pitt 47 for a 1ST down | +21 | 2.95 |
| 7:43 | 1st & 10 | OPP 47 | Wayne Gallman run for 2 yds to the Pitt 45 | +2 | -0.58 |
| 7:12 | 2nd & 8 | OPP 45 | Deshaun Watson pass complete to Ray-Ray McCloud for 1 yd to the Pitt 44 | +1 | -0.87 |
| 6:40 | 3rd & 7 | OPP 44 | Deshaun Watson pass intercepted Avonte Maddox return for no gain to the Pitt 14 | -1.94 |
| 6:32 | 1st & 10 | OWN 14 | James Conner run for 26 yds to the Pitt 40 for a 1ST down | +26 | 1.90 |
| 6:19 | 1st & 10 | OWN 40 | James Conner run for 5 yds to the Pitt 45 | +5 | 0.11 |
| 6:01 | 2nd & 5 | OWN 45 | Nathan Peterman pass complete to Scott Orndoff for 6 yds to the Clem 49 for a 1ST down | +6 | 0.88 |
| 5:34 | 1st & 10 | OPP 49 | Darrin Hall run for 3 yds to the Clem 46 | +3 | -0.38 |
| 4:55 | 2nd & 7 | OPP 46 | Nathan Peterman pass incomplete to Jester Weah | 0 | -1.12 |
| 4:49 | 3rd & 7 | OPP 46 | Peterman, Nathan pass incomplete to Orndoff, Scott, PENALTY CLEMSON pass interference (Smith, Van) 12 yards to the CLEMSON34, NO PLAY, 1ST DOWN PITTSBURGH. | +12 | |
| 4:44 | 1st & 10 | OPP 34 | James Conner run for 27 yds to the Clem 7 for a 1ST down | +27 | 0.74 |
| 4:43 | 1st & goal | OPP 7 | Timeout CLEMSON, clock 04:43 | ||
| 4:36 | 1st & 7 | OPP 7 | Darrin Hall run for a loss of 2 yards to the Clem 9 | -2 | -0.54 |
| 3:42 | 2nd & 9 | OPP 9 | Nathan Peterman run for 8 yds to the Clem 1 | +8 | 0.29 |
| 3:06 | 3rd & 1 | OPP 1 | James Conner run for no gain to the Clem 1 | 0 | -0.33 |
| 2:23 | 4th & 1 | OPP 1 | Nathan Peterman pass complete to George Aston for 1 yd for a TD, (Chris Blewitt KICK) | +1 | 2.79 |
| 2:17 | 1st & 10 | OWN 25 | Deshaun Watson pass complete to Mike Williams for 17 yds to the Clem 42 for a 1ST down | +17 | 1.52 |
| 1:56 | 1st & 10 | OWN 42 | Deshaun Watson run for 8 yds to the 50 yard line | +8 | 0.99 |
| 1:45 | 2nd & 2 | 50 | Deshaun Watson pass complete to Artavis Scott for 10 yds to the Pitt 40 for a 1ST down | +10 | 0.38 |
| 1:40 | 1st & 10 | OPP 40 | Deshaun Watson pass complete to Jordan Leggett for 19 yds to the Pitt 21 for a 1ST down | +19 | 0.56 |
| 1:25 | 1st & 10 | OPP 21 | Deshaun Watson pass complete to Mike Williams for 8 yds to the Pitt 13 | +8 | 0.46 |
| 1:09 | 2nd & 2 | OPP 13 | Deshaun Watson pass complete to Artavis Scott for 13 yds for a TD, (Greg Huegel KICK) | +13 | 2.17 |
| 0:56 | 1st & 10 | OWN 16 | Nathan Peterman pass complete to Jester Weah for 25 yds to the Pitt 41 for a 1ST down | +25 | 1.92 |
| 0:40 | 1st & 10 | OWN 41 | James Conner run for 7 yds to the Pitt 48 | +7 | 0.70 |
| 0:32 | 2nd & 3 | OWN 48 | James Conner run for 1 yd to the Pitt 49 | +1 | -1.03 |
| 0:32 | 3rd & 2 | OWN 49 | Timeout PITTSBURGH, clock 00:32 | ||
| 0:25 | 3rd & 2 | OWN 49 | Darrin Hall run for 8 yds to the Clem 43 for a 1ST down | +8 | 1.64 |
| 0:17 | 1st & 10 | OPP 43 | Nathan Peterman sacked by Carlos Watkins for a loss of 5 yards to the Clem 48 | -5 | -2.05 |
| 0:17 | 2nd & 15 | OPP 48 | Timeout PITTSBURGH, clock 00:17 | ||
| 0:06 | 2nd & 15 | OPP 48 | Nathan Peterman pass complete to Jester Weah for 13 yds to the Clem 35 | +13 | 1.83 |
| 0:05 | 3rd & 2 | OPP 35 | TEAM pass incomplete | 0 | -1.03 |
| 0:00 | 4th & 2 | OPP 35 | Chris Blewitt 53 yd FG BLOCKED blocked by Dexter Lawrence George Aston return for a loss of 4 yards to the Clem 44 | ||
| 0:00 | OPP 0 | End of 2nd Quarter |
| 14:33 | 1st & 10 | OWN 19 | Wayne Gallman run for no gain to the Clem 19 | 0 | -0.53 |
| 14:08 | 2nd & 10 | OWN 19 | Deshaun Watson pass complete to Ray-Ray McCloud for 2 yds to the Clem 21 | +2 | -0.16 |
| 13:40 | 3rd & 8 | OWN 21 | Deshaun Watson pass complete to Ray-Ray McCloud for 9 yds to the Clem 30 for a 1ST down | +9 | 1.44 |
| 13:15 | 1st & 10 | OWN 30 | Wayne Gallman run for 1 yd to the Clem 31 | +1 | -0.72 |
| 13:07 | 2nd & 9 | OWN 31 | Deshaun Watson pass incomplete | 0 | -0.53 |
| 13:03 | 3rd & 9 | OWN 31 | Deshaun Watson pass incomplete to Ray-Ray McCloud | 0 | -0.26 |
| 12:54 | 4th & 9 | OWN 31 | Andy Teasdall punt for 38 yds, downed at the Pitt 31 |
| 12:44 | 1st & 10 | OWN 31 | Nathan Peterman pass complete to Scott Orndoff for 8 yds to the Pitt 39 | +8 | 1.01 |
| 11:53 | 2nd & 2 | OWN 39 | Nathan Peterman pass complete to Aaron Mathews for a loss of 2 yards to the Pitt 37 | -2 | -1.69 |
| 11:17 | 3rd & 4 | OWN 37 | Nathan Peterman pass complete to Dontez Ford for 12 yds to the Pitt 49 for a 1ST down | +12 | 2.36 |
| 10:48 | 1st & 10 | OWN 49 | Nathan Peterman sacked by Dorian O'Daniel for a loss of 2 yards to the Pitt 47 Nathan Peterman fumbled, forced by Dorian O'Daniel, recovered by Clem Dexter Lawrence , return for 0 yards | -2 | -1.59 |
| 10:40 | 1st & 10 | OPP 47 | Deshaun Watson pass complete to Artavis Scott for 5 yds to the Clem 42 CLEMSON Penalty, Offensive Holding (-10 Yards) to the Clem 48 | -5 | -2.16 |
| 10:14 | 1st & 15 | OWN 48 | Deshaun Watson pass complete to Hunter Renfrow for 25 yds to the Pitt 27 for a 1ST down | +25 | 1.99 |
| 9:53 | 1st & 10 | OPP 27 | Deshaun Watson pass complete to Deon Cain for 27 yds for a TD, (Greg Huegel KICK) | +27 | 2.74 |
| 9:26 | 1st & 10 | OWN 25 | James Conner run for 2 yds to the Pitt 27 | +2 | -0.45 |
| 9:00 | 2nd & 8 | OWN 27 | James Conner run for no gain to the Pitt 27 | 0 | -0.48 |
| 8:45 | 3rd & 8 | OWN 27 | Peterman, Nathan pass incomplete to Weah, Jester, PENALTY CLEMSON pass interference (Tankersley, Cordrea) 14 yards to the PITTSBURGH41, NO PLAY, 1ST DOWN PITTSBURGH. | +14 | |
| 8:22 | 1st & 10 | OWN 41 | Nathan Peterman pass complete to James Conner for 13 yds to the Clem 46 for a 1ST down | +13 | 1.12 |
| 7:54 | 1st & 10 | OPP 46 | Nathan Peterman pass complete to Scott Orndoff for 2 yds to the Clem 44 | +2 | -0.57 |
| 7:27 | 2nd & 8 | OPP 44 | Nathan Peterman pass incomplete | 0 | -1.09 |
| 7:02 | 3rd & 8 | OPP 44 | Peterman, Nathan rush for 3 yards to the CLEMSON41, PENALTY CLEMSON offside (Ferrell, Clelin) 5 yards to the CLEMSON39, NO PLAY. | +5 | |
| 6:57 | 3rd & 3 | OPP 39 | Nathan Peterman pass complete to Dontez Ford for 2 yds to the Clem 37 for a 1ST down CLEMSON Penalty, Personal Foul (Ben Boulware) to the Clem 22 for a 1ST down | +17 | 1.38 |
| 6:30 | 1st & 10 | OPP 22 | James Conner run for 5 yds to the Clem 17 | +5 | 0.07 |
| 5:55 | 2nd & 5 | OPP 17 | Nathan Peterman run for 4 yds to the Clem 13 | +4 | -0.03 |
| 5:23 | 3rd & 1 | OPP 13 | James Conner run for 4 yds to the Clem 9 for a 1ST down | +4 | 0.18 |
| 5:05 | 1st & 9 | OPP 9 | James Conner run for 2 yds to the Clem 7 | +2 | -0.18 |
| 4:35 | 2nd & 7 | OPP 7 | Nathan Peterman pass complete to Scott Orndoff for 7 yds for a TD, (Chris Blewitt KICK) | +7 | 2.61 |
| 4:30 | 1st & 10 | OWN 19 | Deshaun Watson pass complete to Mike Williams for 9 yds to the Clem 28 | +9 | 1.08 |
| 4:00 | 2nd & 1 | OWN 28 | Deshaun Watson pass complete to Artavis Scott for 9 yds to the Clem 37 for a 1ST down | +9 | 0.31 |
| 3:43 | 1st & 10 | OWN 37 | Deshaun Watson pass complete to Mike Williams for 15 yds to the Pitt 48 for a 1ST down | +15 | 1.36 |
| 3:21 | 1st & 10 | OPP 48 | Wayne Gallman run for 6 yds to the Pitt 42 | +6 | 0.33 |
| 2:49 | 2nd & 4 | OPP 42 | Deshaun Watson pass complete to Artavis Scott for 28 yds to the Pitt 14 for a 1ST down | +28 | 0.81 |
| 2:20 | 1st & 10 | OPP 14 | Deshaun Watson pass complete to Artavis Scott for 3 yds to the Pitt 11 | +3 | -0.10 |
| 1:58 | 2nd & 7 | OPP 11 | Deshaun Watson pass complete to Hunter Renfrow for 10 yds to the Pitt 1 for a 1ST down | +10 | 1.71 |
| 1:37 | 1st & 1 | OPP 1 | Wayne Gallman run for 1 yd for a TD, (Greg Huegel KICK) | +1 | 0.94 |
| 1:31 | 1st & 10 | OWN 25 | Nathan Peterman pass incomplete to Jester Weah | 0 | -0.70 |
| 1:06 | 2nd & 10 | OWN 25 | Nathan Peterman pass complete to George Aston for a loss of 1 yard to the Pitt 24 | -1 | -0.39 |
| 0:44 | 3rd & 11 | OWN 24 | Nathan Peterman pass incomplete to Dontez Ford | 0 | -0.13 |
| 0:35 | 4th & 11 | OWN 24 | Ryan Winslow punt for 44 yds , Ray-Ray McCloud returns for a loss of 1 yard to the Clem 31 |
| 0:15 | 1st & 10 | OWN 31 | Deshaun Watson pass complete to Jordan Leggett for 11 yds to the Clem 42 for a 1ST down | +11 | 1.05 |
| 0:10 | 1st & 10 | OWN 42 | Deshaun Watson pass incomplete to Deon Cain | 0 | -1.15 |
| 0:02 | 2nd & 10 | OWN 42 | Deshaun Watson pass complete to Wayne Gallman for 7 yds to the Clem 49 | +7 | 0.55 |
| 0:00 | OWN 0 | End of 3rd Quarter | |||
| 14:55 | 3rd & 3 | OWN 49 | Deshaun Watson pass incomplete to Wayne Gallman | 0 | -1.02 |
| 14:48 | 4th & 3 | OWN 49 | Andy Teasdall punt for 40 yds, fair catch by Quadree Henderson at the Pitt 11 |
| 14:41 | 1st & 10 | OWN 11 | James Conner run for a loss of 2 yards to the Pitt 9 | -2 | -0.45 |
| 13:55 | 2nd & 12 | OWN 9 | Quadree Henderson run for a loss of 5 yards to the Pitt 4 | -5 | -0.16 |
| 13:16 | 3rd & 17 | OWN 4 | Nathan Peterman pass incomplete to Quadree Henderson | 0 | -0.02 |
| 13:08 | 4th & 17 | OWN 4 | Ryan Winslow punt for 39 yds , Ray-Ray McCloud returns for a loss of 1 yard to the Pitt 44 |
| 13:00 | 1st & 10 | OPP 44 | Deshaun Watson pass complete to Hunter Renfrow for 5 yds to the Pitt 39 | +5 | 0.09 |
| 12:39 | 2nd & 5 | OPP 39 | Deshaun Watson pass incomplete to C.J. Fuller | 0 | -0.99 |
| 12:07 | 3rd & 5 | OPP 39 | Deshaun Watson sacked by Matt Galambos and Jeremiah Taleni for a loss of 6 yards to the Pitt 45 | -6 | -2.17 |
| 11:50 | 4th & 11 | OPP 45 | Andy Teasdall punt for 35 yds, fair catch by Quadree Henderson at the Pitt 10 |
| 11:40 | 1st & 10 | OWN 10 | James Conner run for 5 yds to the Pitt 15 | +5 | 0.07 |
| 11:21 | 2nd & 5 | OWN 15 | James Conner run for no gain to the Pitt 15 | 0 | -0.39 |
| 10:44 | 3rd & 5 | OWN 15 | Nathan Peterman pass incomplete to Darrin Hall | 0 | -0.17 |
| 10:33 | 4th & 5 | OWN 15 | Ryan Winslow punt for 43 yds, downed at the Clem 42 |
| 10:15 | 1st & 10 | OWN 42 | Deshaun Watson pass complete to Jordan Leggett for 8 yds to the 50 yard line | +8 | 0.99 |
| 9:59 | 2nd & 2 | 50 | Deshaun Watson pass complete to Hunter Renfrow for 4 yds to the Pitt 46 for a 1ST down | +4 | 0.03 |
| 9:37 | 1st & 10 | OPP 46 | Deshaun Watson pass incomplete to Mike Williams | 0 | -1.03 |
| 9:33 | 2nd & 10 | OPP 46 | Deshaun Watson pass incomplete to Artavis Scott | 0 | -1.07 |
| 9:21 | 3rd & 10 | OPP 46 | Deshaun Watson pass complete to Artavis Scott for 12 yds to the Pitt 34 for a 1ST down | +12 | 2.70 |
| 9:03 | 1st & 10 | OPP 34 | Deshaun Watson pass complete to Artavis Scott for 1 yd to the Pitt 33 | +1 | -0.50 |
| 8:30 | 2nd & 9 | OPP 33 | Deshaun Watson pass complete to Mike Williams for 6 yds to the Pitt 27 | +6 | 0.22 |
| 8:03 | 3rd & 3 | OPP 27 | Deshaun Watson pass complete to Mike Williams for 8 yds to the Pitt 19 for a 1ST down | +8 | 0.62 |
| 7:42 | 1st & 10 | OPP 19 | Deshaun Watson pass incomplete to Artavis Scott | 0 | -0.36 |
| 7:33 | 2nd & 10 | OPP 19 | Deshaun Watson pass complete to Wayne Gallman for a loss of 1 yard to the Pitt 20 | -1 | -0.57 |
| 7:02 | 3rd & 11 | OPP 20 | Deshaun Watson pass complete to Hunter Renfrow for 13 yds to the Pitt 7 for a 1ST down | +13 | 1.34 |
| 6:25 | 1st & 7 | OPP 7 | Wayne Gallman run for 4 yds to the Pitt 3 | +4 | -0.01 |
| 5:42 | 2nd & 3 | OPP 3 | Deshaun Watson pass intercepted Saleem Brightwell return for 70 yds to the Clem 30 | -4.79 |
| 5:37 | 1st & 10 | OPP 30 | Nathan Peterman pass incomplete to Aaron Mathews | 0 | -0.56 |
| 5:31 | 2nd & 10 | OPP 30 | Nathan Peterman pass incomplete to Scott Orndoff | 0 | -0.76 |
| 5:26 | 3rd & 10 | OPP 30 | Peterman, Nathan pass incomplete to Weah, Jester, PENALTY CLEMSON holding 10 yards to the CLEMSON20, NO PLAY, 1ST DOWN PITTSBURGH. | +10 | |
| 5:17 | 1st & 10 | OPP 20 | James Conner run for 20 yds for a TD, (Two-Point Conversion failed ) | +20 | 2.62 |
| 5:07 | 1st & 10 | OWN 23 | Deshaun Watson pass complete to Artavis Scott for 7 yds to the Clem 30 | +7 | 0.57 |
| 4:45 | 2nd & 3 | OWN 30 | Deshaun Watson pass complete to Hunter Renfrow for 11 yds to the Clem 41 for a 1ST down | +11 | 0.98 |
| 4:16 | 1st & 10 | OWN 41 | Deshaun Watson pass complete to Deon Cain for 3 yds to the Clem 44 | +3 | -0.43 |
| 3:42 | 2nd & 7 | OWN 44 | Deshaun Watson pass complete to Mike Williams for 5 yds to the Clem 49 | +5 | 0.10 |
| 3:17 | 3rd & 2 | OWN 49 | Timeout PITTSBURGH, clock 03:17 | ||
| 3:10 | 3rd & 2 | OWN 49 | Deshaun Watson pass complete to Mike Williams for 7 yds to the Pitt 44 for a 1ST down | +7 | 1.58 |
| 2:25 | 1st & 10 | OPP 44 | Wayne Gallman run for a loss of 1 yard to the Pitt 45 | -1 | -1.19 |
| 1:50 | 2nd & 11 | OPP 45 | Deshaun Watson pass complete to Mike Williams for 10 yds to the Pitt 35 | +10 | 1.18 |
| 1:11 | 3rd & 1 | OPP 35 | Timeout CLEMSON, clock 01:11 | ||
| 1:03 | 3rd & 1 | OPP 35 | Wayne Gallman run for no gain to the Pitt 35 | 0 | -1.04 |
| 1:02 | 4th & 1 | OPP 35 | Timeout PITTSBURGH, clock 01:02 | ||
| 1:02 | 4th & 1 | OPP 35 | Timeout CLEMSON, clock 01:02 | ||
| 0:58 | 4th & 1 | OPP 35 | Wayne Gallman run for no gain to the Pitt 35 | 0 | -2.53 |
| 0:52 | 1st & 10 | OWN 36 | Nathan Peterman run for 9 yds to the Pitt 45 | +9 | 1.38 |
| 0:51 | 2nd & 1 | OWN 45 | Timeout PITTSBURGH, clock 00:51 | ||
| 0:41 | 2nd & 1 | OWN 45 | Nathan Peterman pass complete to Scott Orndoff for 21 yds to the Clem 34 for a 1ST down | +21 | 0.83 |
| 0:28 | 1st & 10 | OPP 34 | Nathan Peterman pass complete to Scott Orndoff for 4 yds to the Clem 30 | +4 | -0.06 |
| 0:17 | 2nd & 6 | OPP 30 | Nathan Peterman pass incomplete to Jester Weah | 0 | -0.71 |
| 0:12 | 3rd & 6 | OPP 30 | Nathan Peterman pass incomplete to Dontez Ford | 0 | -0.93 |
| 0:12 | 4th & 6 | OPP 30 | Timeout CLEMSON, clock 00:12 | ||
| 0:06 | 4th & 6 | OPP 30 | Chris Blewitt 48 yd FG GOOD | 0.64 | |
| 0:00 | OPP 0 | End of 4th Quarter |
| 2 | sacks | 2 |
| 6 | plays for loss | 9 |
| 3 | takeaways | 1 |
| 1 | three-and-outs forced | 3 |
| 12 | explosive plays allowed | 11 |
| 6.68 | yards allowed / play | 6.61 |
| 6 of 14 | scoring drives allowed | 6 of 14 |
| Matt Galambos | 12 (5) | 0.5 sk · 1 TFL · 1 QH |
| Avonte Maddox | 11 (9) | 2 TFL · 1 INT |
| Oluwaseun Idowu | 11 (5) | |
| Jordan Whitehead | 9 (7) | |
| Terrish Webb | 9 (4) | |
| Mike Caprara | 6 (3) | |
| Ryan Lewis | 6 (3) | 1 INT |
| Reggie Mitchell | 6 (2) |
| Ben Boulware | 12 (3) | 0.5 TFL |
| Kendall Joseph | 10 (5) | |
| Dorian O'Daniel | 9 (6) | 1 sk · 1.5 TFL · 1 QH |
| Van Smith | 7 (4) | 1 TFL |
| Dexter Lawrence | 6 | |
| Clelin Ferrell | 5 | 0.5 TFL · 1 QH |
| Carlos Watkins | 4 (2) | 1 sk · 1.5 TFL · 1 QH |
| Cordrea Tankersley | 4 (2) | 1 TFL |
| 1 of 2 | field goals | — |
| 5 | punts | 3 |
| 43.4 | punt average | 37.7 |
| 0 | punts inside the 20 | 0 |
| 16 | return yards | 118 |
| own 28 | average drive start | own 50 |
| K | Chris Blewitt | 1/2 FG · long 48 · 4/5 XP |
| P | Ryan Winslow | 5 punts · 43.4 avg |
| KR | Quadree Henderson | 1 ret · 16 yds · long 16 |
| K | Greg Huegel | 6/6 XP |
| P | Andy Teasdall | 3 punts · 37.7 avg |
| KR | Artavis Scott | 6 ret · 123 yds · long 26 |
| KR | Grant Radakovich | 1 ret · -3 yds · long -3 |
| KR | Ray-Ray McCloud | 1 ret · -3 yds |
| PR | Ray-Ray McCloud | 3 ret · 1 yds · long 3 |
| 71 | plays | 95 |
| 469 | yards | 635 |
| 14 | drives | 13 |
| 45% | success rate | 53% |
| 21.62 | total PPA | 21.42 |
| Q1 | Nathan Peterman pass complete to George Aston for 15 yds for a TD, (Chris Blewitt KICK) | 7–0 |
| Q1 | Wayne Gallman run for 1 yd for a TD, (Greg Huegel KICK) | 7–7 |
| Q1 | Nathan Peterman pass complete to James Conner for 46 yds for a TD, (Chris Blewitt KICK) | 14–7 |
| Q1 | Wayne Gallman run for 1 yd for a TD, (Greg Huegel KICK) | 14–14 |
| Q2 | Deshaun Watson pass complete to Mike Williams for 15 yds for a TD, (Greg Huegel KICK) | 21–14 |
| Q2 | Nathan Peterman pass complete to Scott Orndoff for 55 yds for a TD, (Chris Blewitt PAT MISSED) | 20–21 |
| Q2 | Nathan Peterman pass complete to George Aston for 1 yd for a TD, (Chris Blewitt KICK) | 27–21 |
| Q2 | Deshaun Watson pass complete to Artavis Scott for 13 yds for a TD, (Greg Huegel KICK) | 28–27 |
| Q3 | Deshaun Watson pass complete to Deon Cain for 27 yds for a TD, (Greg Huegel KICK) | 35–27 |
| Q3 | Nathan Peterman pass complete to Scott Orndoff for 7 yds for a TD, (Chris Blewitt KICK) | 34–35 |
| Q3 | Wayne Gallman run for 1 yd for a TD, (Greg Huegel KICK) | 42–34 |
| Q4 | James Conner run for 20 yds for a TD, (Two-Point Conversion failed ) | 40–42 |
| Q4 | Chris Blewitt 48 yd FG GOOD | 43–42 |
| Q1 | Nathan Peterman pass complete to James Conner for 46 yds for a TD, (Chris Blewitt KICK) | 4.84 |
| Q4 | Chris Blewitt kickoff for 40 yds , Grant Radakovich return for a loss of 3 yards to the⦠| 4.33 |
| Q2 | Nathan Peterman pass complete to Scott Orndoff for 55 yds for a TD, (Chris Blewitt PAT⦠| 4.28 |
| Q1 | Nathan Peterman pass complete to Jaymar Parrish for 44 yds to the Clem 31 for a 1ST down | 3.94 |
| Q2 | Deshaun Watson pass complete to Jordan Leggett for 29 yds to the Pitt 45 for a 1ST down | 3.33 |
| Q1 | Deshaun Watson pass complete to Mike Williams for 30 yds to the Pitt 19 for a 1ST down | 3.06 |
| 2024 | Clemson 24 – 20 Pittsburgh |
| 2021 | Clemson 17 – 27 Pittsburgh |
| 2020 | Pittsburgh 17 – 52 Clemson |
| 2018 | Clemson 42 – 10 Pittsburgh |
| 1977 | Clemson 3 – 34 Pittsburgh |